一个谷氨酸转运RNA（tRNAGlu）基因在染色体上的定位为1p36。
Chromosomal assignment of a glutamic acid transfer RNA (tRNAGlu) gene to 1p36.
作者信息
Boyd E, Theriault A, Goddard J P, Kalaitsidaki M, Spathas D H, Connor J M
机构信息
Duncan Guthrie Institute of Medical Genetics, Glasgow, UK.
出版信息
Hum Genet. 1989 Jan;81(2):153-6. doi: 10.1007/BF00293892.
A gene for tRNAGlu has been assigned to human chromosome 1p36 by in situ hybridisation using a [3H]-labelled or biotinylated 2.4-kb (human) DNA fragment containing a tRNAGlu gene as a probe. With the biotinylated DNA probe a secondary statistically significant site of hybridisation was observed at 1q21-22 which might represent a pseudogene or related sequence. In fibroblasts from gorilla (Gorilla gorilla) using biotin labelling, a single site of hybridisation occurred at 1qter which provides further support for homology of 1q in the higher apes and human 1p.
通过使用含有tRNAGlu基因的[3H]标记或生物素化的2.4 kb（人类）DNA片段作为探针进行原位杂交，已将tRNAGlu基因定位于人类染色体1p36。使用生物素化的DNA探针时，在1q21 - 22处观察到一个具有统计学意义的二级杂交位点，这可能代表一个假基因或相关序列。在大猩猩（Gorilla gorilla）的成纤维细胞中使用生物素标记时，在1qter处出现一个单一的杂交位点，这为高等猿类的1q与人类1p的同源性提供了进一步的支持。
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