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Regional chromosomal assignment of the human mineralocorticoid receptor gene to 4q31.1.

作者信息

Morrison N, Harrap S B, Arriza J L, Boyd E, Connor J M

机构信息

Duncan Guthrie Institute of Medical Genetics, Yorkhill, Glasgow, UK.

出版信息

Hum Genet. 1990 Jun;85(1):130-2. doi: 10.1007/BF00276340.

DOI:10.1007/BF00276340
PMID:2162806
Abstract

The gene for human mineralocorticoid receptor (hMR), previously mapped to chromosome 4, has been further localized to 4q31.1 by in situ hybridization using a biotinylated 3.75 kb human cDNA clone encoding the primary amino acid sequence of hMR as a probe. Preliminary comparative mapping studies in orangutan (Pongo pygmaeus) suggest localization of the probe to the long arm of chromosome 3.

摘要

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本文引用的文献

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Novel non-isotopic in situ hybridization technique detects small (1 Kb) unique sequences in routinely G-banded human chromosomes: fine mapping of N-myc and beta-NGF genes.新型非同位素原位杂交技术可检测常规G显带人类染色体中的小（1千碱基）独特序列：N-myc和β-神经生长因子基因的精细定位
Nucleic Acids Res. 1987 Jun 25;15(12):4761-70. doi: 10.1093/nar/15.12.4761.
2
Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor.人盐皮质激素受体互补DNA的克隆：与糖皮质激素受体的结构和功能关系
Science. 1987 Jul 17;237(4812):268-75. doi: 10.1126/science.3037703.
3
Chromosomal assignment of a glutamic acid transfer RNA (tRNAGlu) gene to 1p36.
肾脏发育过程中糖皮质激素信号的性别二态性。
Int J Mol Sci. 2021 May 18;22(10):5275. doi: 10.3390/ijms22105275.
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Immune Effects of Corticosteroids in Sepsis.脓毒症中皮质类固醇的免疫作用。
Front Immunol. 2018 Jul 30;9:1736. doi: 10.3389/fimmu.2018.01736. eCollection 2018.
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Zinc Finger Nuclease induced DNA double stranded breaks and rearrangements in MLL.锌指核酸酶诱导 MLL 中的 DNA 双链断裂和重排。
Mutat Res. 2012 Dec;740(1-2):34-42. doi: 10.1016/j.mrfmmm.2012.12.006. Epub 2013 Jan 2.
6
Low renal mineralocorticoid receptor expression at birth contributes to partial aldosterone resistance in neonates.出生时肾脏盐皮质激素受体表达水平低导致新生儿出现部分醛固酮抵抗。
Endocrinology. 2009 Sep;150(9):4414-24. doi: 10.1210/en.2008-1498. Epub 2009 May 28.
7
Central mineralocorticoid receptors, sympathetic activity, and hypertension.中枢盐皮质激素受体、交感神经活动与高血压。
Curr Hypertens Rep. 2009 Jun;11(3):224-30. doi: 10.1007/s11906-009-0039-0.
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The mineralocorticoid receptor: insights into its molecular and (patho)physiological biology.盐皮质激素受体：对其分子及（病理）生理生物学的见解。
Nucl Recept Signal. 2007 Nov 30;5:e012. doi: 10.1621/nrs.05012.
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Corticosteroid receptor genetic polymorphisms and stress responsivity.皮质类固醇受体基因多态性与应激反应性。
Endocrine. 2005 Dec;28(3):263-70. doi: 10.1385/ENDO:28:3:263.
一个谷氨酸转运RNA（tRNAGlu）基因在染色体上的定位为1p36。
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4
Regional chromosomal assignment of the human glucocorticoid receptor gene to 5q31.
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5
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Cytogenet Cell Genet. 1989;52(1-2):83-4. doi: 10.1159/000132846.