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1470纳米激光汽化术治疗良性前列腺增生的综述

Critical reviews of 1470-nm laser vaporization on benign prostatic hyperplasia.

作者信息

Liu Zhifeng, Zhao Yongwei, Wang Xingliang, Song Mingshan, Shi Benkang

机构信息

Department of Urology, Qilu Hospital of Shandong University, 107 West Wenhua Road, Jinan, Shandong, 250012, People's Republic of China.

Department of Urology, Taian City Central Hospital, Taian, Shandong, 271000, China.

出版信息

Lasers Med Sci. 2018 Feb;33(2):323-327. doi: 10.1007/s10103-017-2377-5. Epub 2017 Nov 11.

Abstract

Benign prostatic hyperplasia (BPH) is recognized as the common chronic disease that affect majority of men in their elder ages. Nevertheless, there are no effective documents for BPH treatment. Even though great progression has been made on BPH by laser surgery, it also faces several challenges. In this study, our aims were to explore the effects of 1470-nm laser vaporization on BPH. For the research, a total of 170 BPH patients were enrolled. A 1470-nm laser vaporization apparatus was purchased for the surgery. The indicators such as serum sodium, international prostate symptom score (IPSS), Quality of life (QOL), maximum flow rate (Qmax), prostate specific antigen (PSA), and average Post-void Residual Volume (PVR) were detected for evaluating the prostate function. The operation was successful in all 170 patients, neither of whom converted to transurethral resection of the prostate (TURP) nor to open surgery. The surgery time was 52.3 ± 5.6 min, the laser emission time was 35.6 ± 3.2 min, the energy consumption was 254.1 ± 19.3 kJ. The level of serum sodium showed no significant difference between the pre- and post-operation. Qmax was significantly increased in post-operation, while IPSS, QOL, PVR, and PSA were significantly decreased in the post-operation. The 1470-nm laser vaporization treatment protected patients against BPH, indicating that 1470-nm laser vaporization might be important on treating BPH, which provided solid foundation for further clinical treatment.

摘要

良性前列腺增生(BPH)被认为是影响大多数老年男性的常见慢性疾病。然而,目前尚无有效的BPH治疗文献。尽管激光手术在BPH治疗方面取得了很大进展,但仍面临一些挑战。在本研究中,我们的目的是探讨1470纳米激光汽化术对BPH的影响。为了进行这项研究,共纳入了170例BPH患者。购买了一台1470纳米激光汽化设备用于手术。检测血清钠、国际前列腺症状评分(IPSS)、生活质量(QOL)、最大尿流率(Qmax)、前列腺特异性抗原(PSA)和平均残余尿量(PVR)等指标以评估前列腺功能。170例患者手术均成功,无一例转为经尿道前列腺切除术(TURP)或开放手术。手术时间为52.3±5.6分钟,激光发射时间为35.6±3.2分钟,能量消耗为254.1±19.3千焦。血清钠水平术前和术后无显著差异。术后Qmax显著增加,而术后IPSS、QOL、PVR和PSA显著降低。1470纳米激光汽化治疗对BPH患者有保护作用,表明1470纳米激光汽化术在BPH治疗中可能具有重要意义,为进一步的临床治疗提供了坚实的基础。

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