Guarino A, Giannella R, Thompson M R
Department of Internal Medicine, University of Cincinnati College of Medicine, Ohio 45267.
Infect Immun. 1989 Feb;57(2):649-52. doi: 10.1128/iai.57.2.649-652.1989.
We purified and sequenced the heat-stable enterotoxin produced by Citrobacter freundii. The toxin was detected during purification by reaction with monoclonal antibody to Escherichia coli heat-stable enterotoxin. The C. freundii toxin amino acid sequence was identical to that of the 18-amino-acid heat-stable enterotoxin (STa) produced by toxigenic E. coli.
我们纯化并测序了弗氏柠檬酸杆菌产生的热稳定肠毒素。在纯化过程中,通过与抗大肠杆菌热稳定肠毒素的单克隆抗体反应检测到了该毒素。弗氏柠檬酸杆菌毒素的氨基酸序列与产毒素大肠杆菌产生的18氨基酸热稳定肠毒素(STa)的序列相同。