Department of Pharmacy, Pharmacology and Postgraduate Medicine, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, UK.
College of Pharmacy, King Saud University, Riyadh, Riyadh, Saudi Arabia.
BMJ Open. 2017 Nov 12;7(11):e017664. doi: 10.1136/bmjopen-2017-017664.
To investigate the factors contributing to medicine-related problems (MRPs) among patients with cardiovascular diseases (CVDs) and/or diabetes in Saudi Arabia.
Qualitative semistructured interviews were conducted. Interviews were audio recorded then transcribed into Microsoft Word. The transcribed interviews were then imported into the qualitative analysis software NVivo where thematic analysis was applied. Thematic synthesis was achieved by coding and developing subthemes/themes from the findings of the interviews.
Five healthcare centres in Najran, Saudi Arabia.
25 adult patients with diabetes and/or CVDs.
The study cohort included 16 men and 9 women with a median age of 61.8 years (40-85 years). Diabetes was the main condition encountered among 23 patients and CVDs were reported among 18 patients. Perceived factors leading to MRPs were of four types and related to: patient-, healthcare system-, clinical (condition-) and medicine-related factors. Patient-related factors were related to living situation, religious practices, diet/exercise and patients' behaviour towards the condition and medicines. Healthcare system-related factors comprised sources and availability of medicines, ease of access to healthcare system and patient satisfaction with healthcare providers. Clinical (condition-) related factors associated with both the knowledge and control over condition, and effects of the condition among medicines intake. Medicine-related factors included lack of knowledge about medicines and medicine use.
The results of this study uncovered many factors associated with MRPs among patients with CVDs and diabetes in Saudi Arabia, especially in reference to lifestyle and medicine use. Improving communication with healthcare professional alongside the introduction of national clinical guidance would mitigate the unwanted health complications related to medicine use.
调查导致沙特阿拉伯心血管疾病（CVD）和/或糖尿病患者出现药物相关问题（MRP）的因素。
进行定性半结构式访谈。访谈进行录音，然后转录为 Microsoft Word。将转录的访谈导入定性分析软件 NVivo 中，应用主题分析。通过对访谈结果进行编码和开发子主题/主题，实现主题综合。
沙特阿拉伯纳季兰的五家医疗中心。
25 名患有糖尿病和/或 CVD 的成年患者。
研究队列包括 16 名男性和 9 名女性，中位年龄为 61.8 岁（40-85 岁）。23 名患者的主要疾病是糖尿病，18 名患者报告患有 CVD。导致 MRP 的感知因素有四种类型，与患者、医疗保健系统、临床（病情）和药物相关因素有关。与患者相关的因素与生活状况、宗教习俗、饮食/运动以及患者对病情和药物的行为有关。与医疗保健系统相关的因素包括药物的来源和可获得性、获得医疗保健系统的便利性以及患者对医疗保健提供者的满意度。与临床（病情）相关的因素与对病情的了解和控制以及病情对药物摄入的影响有关。与药物相关的因素包括对药物的了解不足和用药不当。
这项研究的结果揭示了许多与沙特阿拉伯 CVD 和糖尿病患者出现 MRP 相关的因素，特别是与生活方式和药物使用有关。改善与医疗保健专业人员的沟通，并引入国家临床指南，将减轻与药物使用相关的不良健康并发症。
