Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University Medical Center Ulm, Ulm, Germany.
Clin Cancer Res. 2018 Feb 1;24(3):505-507. doi: 10.1158/1078-0432.CCR-17-2991. Epub 2017 Nov 13.
For the first time, human papillomavirus (HPV)-specific immunity has been linked directly to the beneficial prognosis of oropharyngeal squamous cell carcinoma (OPSCC). Those patients lacking HPV immunity fare much worse. These results harbor crucial implications for future management of HPV-driven OPSCC as well as for its definition. .
人类乳头瘤病毒(HPV)特异性免疫与口咽鳞状细胞癌(OPSCC)的良好预后首次直接相关。那些缺乏 HPV 免疫的患者预后要差得多。这些结果对 HPV 驱动的 OPSCC 的未来管理以及其定义具有重要意义。