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药物基因变异(PharmVar)联盟:纳入人类细胞色素 P450(CYP)等位基因命名数据库。

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database.

机构信息

Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Kansas City, and School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.

Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.

出版信息

Clin Pharmacol Ther. 2018 Mar;103(3):399-401. doi: 10.1002/cpt.910. Epub 2017 Nov 14.

Abstract

The Human Cytochrome P450 (CYP) Allele Nomenclature Database, a critical resource for the pharmacogenetics and genomics communities, has transitioned to the Pharmacogene Variation (PharmVar) Consortium. In this report we provide a summary of the current database, provide an overview of the PharmVar consortium, and highlight the PharmVar database which will serve as the new home for pharmacogene nomenclature.

摘要

人类细胞色素 P450(CYP)基因座命名数据库是药物遗传学和基因组学领域的重要资源,现已过渡到药物基因变异(PharmVar)联盟。在本报告中,我们总结了当前数据库,概述了 PharmVar 联盟,并重点介绍了 PharmVar 数据库,它将成为药物基因命名的新家园。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e05/5836850/f69ad148257c/CPT-103-399-g001.jpg

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