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刚果民主共和国伤寒沙门氏菌血清型 Typhi 产生 CTX-M-15 型超广谱β-内酰胺酶。

Salmonella enterica serovar Typhi Producing CTX-M-15 Extended Spectrum β-Lactamase in the Democratic Republic of the Congo.

机构信息

National Institute for Biomedical Research.

Department of Microbiology, University Teaching Hospital of Kinshasa, Democratic Republic of the Congo.

出版信息

Clin Infect Dis. 2017 Oct 1;65(7):1229-1231. doi: 10.1093/cid/cix342.

DOI:10.1093/cid/cix342
PMID:29136410
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5849100/
Abstract

We report a typhoid fever case with a Salmonella enterica serovar Typhi isolate showing extended spectrum β-lactamase (ESBL) production in the Democratic Republic of the Congo. Whole genome sequencing revealed that the strain carried a plasmid-mediated CTX-M-15 ESBL gene and did not belong to the dominant H58 Salmonella Typhi clade.

摘要

我们报告了一例伤寒病例,该病例的伤寒沙门氏菌血清型 Typhi 分离株产生了超广谱β-内酰胺酶(ESBL)。全基因组测序显示,该菌株携带一种质粒介导的 CTX-M-15 ESBL 基因,不属于主要的 H58 伤寒沙门氏菌群。

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Ceftriaxone-resistant Salmonella enterica serotype typhimurium sequence type 313 from Kenyan patients is associated with the blaCTX-M-15 gene on a novel IncHI2 plasmid.来自肯尼亚患者的对头孢曲松耐药的鼠伤寒沙门氏菌血清型313序列型313与一种新型IncHI2质粒上的blaCTX-M-15基因相关。
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