Gambino Caterina M, Accardi Giulia, Aiello Anna, Candore Giuseppina, Dara-Guccione Giovanni, Mirisola Mario, Procopio Antonio, Taormina Giusi, Caruso Calogero
Dipartimento di Biopatologia e Biotecnologie Mediche, Universita degli studi di Palermo, Palermo, Italy.
CREA Centro di ricerca Politiche e Bio-economia, Rome, Italy.
Endocr Metab Immune Disord Drug Targets. 2018;18(1):14-22. doi: 10.2174/1871530317666171114113822.
Extra virgin olive oil (EVOO) is the common element among the Mediterranean countries. It can be considered a nutraceutical and functional food, thanks to its bioactive compounds. It can act and modulate different processes linked to ageing and age-related diseases related to a common chronic low grade inflammation. Depending on the cultivar, the growth conditions, the period of harvesting, the productive process and time of product storage, EVOO could contain different amount of vegetal components. Of course, the same is for table olives.
The aim of our review is to summarize the effects of EVOO and table olives on the immunemediated inflammatory response, focusing our attention on human studies.
Our report highlights the effect of specific molecules obtained from EVOO on the modulation of specific cytokines and anti-oxidants suggesting the importance of the daily consumption of both EVOO and table olives in the context of a Mediterranean dietary pattern. In addition, the different action on immune-inflammatory biomarkers, are depending on the olive tree cultivar.
Thanks to their bioactive compounds, EVOO and table olive can be considered as nutraceutical and functional foods. The beneficial effects analysed in this review will help to understand the potential application of specific olive components as therapeutic adjuvant, supplements or drugs.
特级初榨橄榄油(EVOO)是地中海国家的常见元素。由于其生物活性化合物,它可被视为一种营养保健品和功能性食品。它能够作用并调节与衰老以及与常见慢性低度炎症相关的年龄相关性疾病有关的不同过程。根据品种、生长条件、收获时期、生产工艺和产品储存时间的不同,EVOO可能含有不同量的植物成分。当然,食用橄榄也是如此。
我们综述的目的是总结EVOO和食用橄榄对免疫介导的炎症反应的影响,重点关注人体研究。
我们的报告强调了从EVOO中获得的特定分子对特定细胞因子和抗氧化剂的调节作用,表明在地中海饮食模式中每日食用EVOO和食用橄榄的重要性。此外,对免疫炎症生物标志物的不同作用取决于橄榄树品种。
由于其生物活性化合物,EVOO和食用橄榄可被视为营养保健品和功能性食品。本综述中分析的有益作用将有助于理解特定橄榄成分作为治疗辅助剂、补充剂或药物的潜在应用。