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特级初榨橄榄油与心血管疾病:对人类健康的益处

Extra Virgin Olive Oil and Cardiovascular Diseases: Benefits for Human Health.

作者信息

Nocella Cristina, Cammisotto Vittoria, Fianchini Luca, D'Amico Alessandra, Novo Marta, Castellani Valentina, Stefanini Lucia, Violi Francesco, Carnevale Roberto

机构信息

Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Rome, Italy.

Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy.

出版信息

Endocr Metab Immune Disord Drug Targets. 2018;18(1):4-13. doi: 10.2174/1871530317666171114121533.

Abstract

BACKGROUND AND OBJECTIVE

The cardioprotective properties of Mediterranean Diet were demonstrated for the first time from the Seven Country Study. In the last few decades, numerous epidemiological studies, as well as intervention trial, confirmed this observation, pointing out the close relationship between the Mediterranean diet and cardiovascular diseases. In this context, extra virgin olive oil (EVOO), the most representative component of this diet, seems to be relevant in lowering the incidence of cardiovascular events, including myocardial infarction and stroke. From a chemical point of view, 98-99% of the total weight of EVOO is represented by fatty acids, especially monounsaturated fatty acids such as oleic acid. Tocopherols, polyphenols and other minor constituents represent the remaining 1-2%. All these components may potentially contribute to "health maintenance" with their beneficial effects by EVOOO.

METHODS

Studies that examined the effect of EVOO supplementation in healthy subjects and in individuals at cardiovascular risk were included.

CONCLUSION

The studies analyzed demonstrated the role of EVOO as anti-inflammatory, antioxidant and vasodilatory nutrient that may contribute to lower the atherosclerotic burden.

摘要

背景与目的

地中海饮食的心脏保护特性首次在七国研究中得到证实。在过去几十年里,众多流行病学研究以及干预试验均证实了这一观察结果,指出地中海饮食与心血管疾病之间存在密切关系。在此背景下,特级初榨橄榄油(EVOO)作为这种饮食最具代表性的成分,似乎在降低心血管事件(包括心肌梗死和中风)的发生率方面具有重要意义。从化学角度来看,EVOO总重量的98 - 99%由脂肪酸组成,尤其是单不饱和脂肪酸,如油酸。生育酚、多酚和其他微量成分占其余的1 - 2%。所有这些成分可能通过EVOO的有益作用对“健康维持”有潜在贡献。

方法

纳入了研究EVOO补充剂对健康受试者和心血管疾病风险个体影响的研究。

结论

分析的研究表明EVOO作为抗炎、抗氧化和血管舒张性营养素的作用,这可能有助于减轻动脉粥样硬化负担。

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