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具有抗衰老特性的植物化学物质的 hormetic 效应 。 (注:hormetic 这个词在医学领域可能有特定含义,这里直接保留英文,因为可能没有完全对应的中文词汇,具体需结合专业语境理解。)

Hormetic Effects of Phytochemicals with Anti-Ageing Properties.

作者信息

Caruso Calogero, Accardi Giulia, Aiello Anna, Candore Giuseppina

机构信息

Laboratory of Immunopathology and Immunosenescence, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Palermo, Italy.

出版信息

Subcell Biochem. 2024;107:205-215. doi: 10.1007/978-3-031-66768-8_10.

DOI:10.1007/978-3-031-66768-8_10
PMID:39693026
Abstract

In the fields of biology and medicine, hormesis is defined as the adaptive response of cells and organisms to moderate and usually intermittent stress. Examples include radiation, pharmaceutical agents, as well as dietary and lifestyle factors such as calorie restriction and physical exercise. However, in the present chapter, we will focus on the hormetic role of certain phytochemicals, compounds that naturally occur in plants, playing roles in plant colour, flavour, and disease resistance, with nutraceutical properties. Indeed, these compounds exhibit health-promoting, disease-preventing, or medicinal properties, mostly through a hormetic mechanism.

摘要

在生物学和医学领域,毒物兴奋效应被定义为细胞和生物体对适度且通常是间歇性应激的适应性反应。例子包括辐射、药剂,以及饮食和生活方式因素,如热量限制和体育锻炼。然而,在本章中,我们将聚焦于某些植物化学物质的毒物兴奋效应作用,这些化合物天然存在于植物中,在植物颜色、风味和抗病性方面发挥作用,并具有营养保健特性。事实上,这些化合物大多通过毒物兴奋效应机制展现出促进健康、预防疾病或药用特性。

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Hormetic Effects of Phytochemicals with Anti-Ageing Properties.具有抗衰老特性的植物化学物质的 hormetic 效应 。 (注:hormetic 这个词在医学领域可能有特定含义,这里直接保留英文,因为可能没有完全对应的中文词汇,具体需结合专业语境理解。)
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本文引用的文献

1
Hormesis determines lifespan.毒物兴奋效应决定寿命。
Ageing Res Rev. 2024 Feb;94:102181. doi: 10.1016/j.arr.2023.102181. Epub 2024 Jan 3.
2
Healthy ageing and Mediterranean diet: A focus on hormetic phytochemicals.健康老龄化与地中海饮食:聚焦具有 hormetic 效应的植物化学物质。
Mech Ageing Dev. 2021 Dec;200:111592. doi: 10.1016/j.mad.2021.111592. Epub 2021 Oct 25.
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Inflammaging, hormesis and the rationale for anti-aging strategies.慢性炎症、应激与抗衰老策略的原理。
Ageing Res Rev. 2020 Dec;64:101142. doi: 10.1016/j.arr.2020.101142. Epub 2020 Aug 16.
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Phytochemicals as Prebiotics and Biological Stress Inducers.作为益生元和生物应激诱导剂的植物化学物质。
Trends Biochem Sci. 2020 Jun;45(6):462-471. doi: 10.1016/j.tibs.2020.02.008. Epub 2020 Mar 17.
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Deciphering the Role of Polyphenols in Sports Performance: From Nutritional Genomics to the Gut Microbiota toward Phytonutritional Epigenomics.解析多酚在运动表现中的作用:从营养基因组学到肠道微生物群,再到植物营养素表观基因组学。
Nutrients. 2020 Apr 29;12(5):1265. doi: 10.3390/nu12051265.
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Healthy Effects of Plant Polyphenols: Molecular Mechanisms.植物多酚的健康效应:分子机制。
Int J Mol Sci. 2020 Feb 13;21(4):1250. doi: 10.3390/ijms21041250.
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Current nutritional and pharmacological anti-aging interventions.当前的营养和药理学抗衰老干预措施。
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Hormetic Effects of Phytochemicals on Health and Longevity.植物化学物的健康与长寿的应激效应。
Trends Endocrinol Metab. 2019 Jun;30(6):335-346. doi: 10.1016/j.tem.2019.04.001. Epub 2019 May 3.
9
Genotypic and Phenotypic Aspects of Longevity: Results from a Sicilian Survey and Implication for the Prevention and Treatment of Age-related Diseases.长寿的基因型和表型方面:来自西西里岛调查的结果及其对与年龄相关疾病的预防和治疗的意义。
Curr Pharm Des. 2019;25(3):228-235. doi: 10.2174/1381612825666190313115233.
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Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential.热量限制类似物防治与年龄相关的疾病:靶点、机制和治疗潜力。
Cell Metab. 2019 Mar 5;29(3):592-610. doi: 10.1016/j.cmet.2019.01.018.