Screening of Norharmane from Seven Cyanobacteria by High-performance Liquid Chromatography.

BACKGROUND

Cyanobacteria, including pharmaceutically and medicinally valuable compounds attract the great attention lately. Norharmane (9H-pyrido (3,4-b) indole found in some cyanobacteria revealed a great number of biological effects.

OBJECTIVE

Seven cyanobacteria were isolated and identified from Yesilirmak River and Gaziosmanpasa University Campus to determine the norharmane content.

MATERIALS AND METHODS

Cyanobacteria collected from Tokat, Turkey were isolated and identified by morphologically. Norharmane (9H-pyrido [3,4-b] indole) quantities were presented for seven cyanobacteria, (Kütz.) Nägeli, (Geitler) Anagnostidis, Bornet ex Bornet and Flahault, F. E. Fritsch, Lemmermann, . Kützing ex Gomont, and . Kutzing ex E. Bornet and by high-performance liquid chromatography.

RESULTS

The norharmane amount indicated for cyanobacterial culture media altered in a species-dependent kind in the range of 0.81-10.87 μg/g. produced the most norharmane among the investigated cyanobacteria as 10.87 μg/g.

CONCLUSION

Cyanobacteria could be an important source of norharmane as well as pharmaceutically valuable compounds.

SUMMARY

Seven cyanobacteria were isolated and identified from Yesilirmak RiverQuantitative analysis of norharmane was executed on isolated cyanobacteriaFour cyanobecteria species included the norharmane contained the most norharmane (10.87 μg/g). HPLC: High performance liquid chromatograph.