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多发性硬化症中的运动疗法及其对功能和大脑的影响。

Exercise therapy in multiple sclerosis and its effects on function and the brain.

作者信息

Dalgas Ulrik

机构信息

Department of Public Health, Section of Sport Science, Aarhus University, Denmark.

出版信息

Neurodegener Dis Manag. 2017 Nov;7(6s):35-40. doi: 10.2217/nmt-2017-0040.

DOI:10.2217/nmt-2017-0040
PMID:29143590
Abstract

Exercise therapy is a promising nonpharmacological therapy in people with multiple sclerosis (MS). Although exercise training may induce a transient worsening of symptoms in some MS patients, it is generally considered safe and does not increase the risk of relapses. Exercise training can lead to clinically relevant improvements in physical function, but should be considered an adjunct to specific task-based training. Exercise has also shown positive effects on the brain, including improvements in brain volume and cognition. In summary, exercise therapy is a safe and potent nonpharmacological intervention in MS, with beneficial effects on both functional capacity and the brain.

摘要

运动疗法对多发性硬化症(MS)患者而言是一种很有前景的非药物疗法。尽管运动训练可能会在一些MS患者中导致症状短暂加重,但一般认为它是安全的,且不会增加复发风险。运动训练可在身体功能方面带来具有临床意义的改善,但应被视为基于特定任务训练的辅助手段。运动对大脑也显示出积极影响,包括脑容量和认知能力的改善。总之,运动疗法是MS中一种安全且有效的非药物干预措施,对功能能力和大脑均有有益作用。

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