Rogers P L, Lane H C, Henderson D K, Parrillo J, Masur H
Critical Care Medicine Department, National Institute of Allergy and Infectious Disease, Bethesda, MD.
Crit Care Med. 1989 Feb;17(2):113-7. doi: 10.1097/00003246-198902000-00001.
As the number of cases of AIDS increases, it is important to determine whether ICUs can be productively and safely used for this patient population. From July 1981 to March 1987, 216 patients were admitted to the medical ICU: 166 (77%) were admitted for procedures and 50 (23%) were admitted for life-sustaining support. Most of the patients were admitted for respiratory failure (36 of 50), primarily as a result of Pneumocystis carinii pneumonia. Other patients were admitted for cardiovascular instability (six of 50 patients), CNS dysfunction (four patients), or other reasons (four patients). Of 50 patients admitted to the ICU, 13 (26%) were alive 3 months after hospital discharge. Despite 25 needle-stick injuries and 56 mucosal splashes involving human immunodeficiency virus (HIV)-infected patients and staff, no staff member converted HIV serology. These results suggest that AIDS patients may benefit from ICU admission. These patients appear to pose a low risk to the hospital staff in terms of occupationally acquired HIV infection, but strong emphasis needs to be placed on minimizing accidental exposures to potentially infected body fluids and to adhering to universal precautions.
随着艾滋病病例数量的增加,确定重症监护病房(ICU)是否能有效地、安全地用于这类患者群体显得尤为重要。从1981年7月至1987年3月,216例患者被收治入内科重症监护病房:166例(77%)因手术入院,50例(23%)因生命维持支持入院。大多数患者因呼吸衰竭入院(50例中的36例),主要是由于卡氏肺孢子虫肺炎。其他患者因心血管功能不稳定入院(50例患者中的6例)、中枢神经系统功能障碍(4例患者)或其他原因(4例患者)。在50例入住ICU的患者中,13例(26%)在出院3个月后仍存活。尽管有25例针刺伤和56例黏膜接触溅到涉及感染人类免疫缺陷病毒(HIV)的患者和工作人员,但没有工作人员HIV血清学转化。这些结果表明,艾滋病患者可能从入住ICU中获益。就职业性获得HIV感染而言,这些患者似乎对医院工作人员构成的风险较低,但需要大力强调尽量减少意外接触潜在感染体液并坚持普遍预防措施。