两例病例报告：儿童结直肠癌
Two case reports: Colorectal adenocarcinoma in children.
作者信息
Ahn Chang Hoon, Kim Soon Chul
机构信息
Department of Pediatrics, Chonbuk National University Medical School and Hospital, Research Institute of Clinical Medicine of Chonbuk National University - Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
出版信息
Medicine (Baltimore). 2017 Nov;96(46):e8074. doi: 10.1097/MD.0000000000008074.
RATIONALE
Colorectal cancer in children is rare, with delayed diagnosis and advanced stage at presentation in high mortality. Early detection of colorectal cancer is, therefore, important for better prognosis.
PATIENT CONCERNS
Thirteen-year-old boy presented with symptoms of melena, vomiting, and abdominal pain for 6 months. 18-year-old girl was hospitalized due to the symptoms of hematochezia, and persistent abdominal pain for 6 months. They have no chronic disease or familial history of malignancy.
DIAGNOSES
We encountered 2 teenagers diagnosed with colorectal cancer.
INTERVENTIONS
Both patients had the same histological findings in postoperation colonic biopsy and underwent surgical resection.
OUTCOMES
The boy fully recovered with only surgery, but the girl died, despite receiving adjuvant chemotherapy for the advanced stage of cancer.
LESSONS
We recommend early and active evaluation, including a pediatric colonoscopy, in a child with suspected malignancy.
理论依据
儿童结直肠癌较为罕见，诊断延迟且就诊时多为晚期，死亡率高。因此，早期发现结直肠癌对于改善预后很重要。
患者情况
一名13岁男孩出现黑便、呕吐和腹痛症状6个月。一名18岁女孩因便血和持续腹痛症状住院6个月。他们无慢性疾病或恶性肿瘤家族史。
诊断
我们遇到2名被诊断为结直肠癌的青少年。
干预措施
两名患者术后结肠活检的组织学结果相同，并均接受了手术切除。
结果
男孩仅通过手术完全康复，但女孩尽管因癌症晚期接受了辅助化疗仍死亡。
经验教训
对于疑似患有恶性肿瘤的儿童，我们建议进行早期积极评估，包括小儿结肠镜检查。
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