School of Psychology and Illawarra Health and Medical Research Institute, University of Wollongong, Northfields Ave, Wollongong, NSW 2522, Australia.
School of Psychology and Illawarra Health and Medical Research Institute, University of Wollongong, Northfields Ave, Wollongong, NSW 2522, Australia.
Drug Alcohol Depend. 2018 Jan 1;182:58-66. doi: 10.1016/j.drugalcdep.2017.10.008. Epub 2017 Nov 12.
Difficulties in emotion regulation influence the development of substance use disorder (SUD), its severity, course, treatment outcomes, and relapse. Impaired executive functions (EFs) are common in SUD populations and may relate to emotion dysregulation. The current study tested whether performance on three basic EF tasks ('working memory', 'inhibition', and 'task-switching') and/or inventory-based assessment of EF were related to difficulties in emotion regulation in females attending residential SUD therapeutic community treatment.
Cross-sectional design in which participants (N=50, all female) completed a questionnaire battery including the Difficulties in Emotion Regulation Scale (DERS) and Behavior Rating Inventory of Executive Function - Adult Version (BRIEF-A) was used. Participants also completed neuropsychological assessment of EF including the Working Memory Index (WMI; Wechsler Adult Intelligence Scale), and measures of inhibition and task-switching (Color-Word Interference Test; Delis-Kaplan Executive Function System).
Executive dysfunction, as assessed by the Global Executive Composite (GEC; BRIEF-A), and personality disorder indicators (Standardised Assessment of Personality - Abbreviated Scale; SAPAS) were positively correlated with DERS scores. Sequential hierarchical regression indicated that task-switching, GEC, and SAPAS scores statistically predicted DERS scores, while working memory and inhibition did not. Mediation analysis indicated that there was a significant indirect effect of GEC scores and task-switching performance on DERS scores, through SAPAS scores.
Impairment of EF, particularly task-switching, is related to difficulties in emotion regulation in a female sample attending residential SUD treatment. Cognitive training interventions that improve task-switching performance may be beneficial in promoting effective emotion regulation and improved SUD treatment outcomes.
情绪调节困难会影响物质使用障碍（SUD）的发展、严重程度、病程、治疗效果和复发。执行功能障碍（EF）在 SUD 人群中很常见，可能与情绪失调有关。本研究旨在测试在参加住院 SUD 治疗社区治疗的女性中，三种基本 EF 任务（“工作记忆”、“抑制”和“任务转换”）和/或基于清单的 EF 评估的表现是否与情绪调节困难有关。
采用横断面设计，参与者（N=50，均为女性）完成了一个问卷测试，包括情绪调节困难量表（DERS）和行为评定量表修订版成人版（BRIEF-A）。参与者还完成了 EF 的神经心理学评估，包括工作记忆指数（WMI；韦氏成人智力量表）以及抑制和任务转换的测量（颜色-单词干扰测试；德里斯科尔执行功能系统）。
以 BRIEF-A 的总体执行综合评分（GEC）和人格障碍指标（简化人格评估量表-缩写版；SAPAS）评估的执行功能障碍与 DERS 评分呈正相关。逐步分层回归表明，任务转换、GEC 和 SAPAS 评分可预测 DERS 评分，而工作记忆和抑制则不能。中介分析表明，GEC 评分和任务转换表现对 DERS 评分的影响存在显著的间接效应，通过 SAPAS 评分。
EF 受损，特别是任务转换，与参加住院 SUD 治疗的女性的情绪调节困难有关。提高任务转换表现的认知训练干预可能有助于促进有效的情绪调节和改善 SUD 治疗效果。
