Bayer A/S Division Crop Science, Arne Jacobsens Allé 13, 2300 Copenhagen S, Denmark.
Bayer A/S Division Crop Science, Arne Jacobsens Allé 13, 2300 Copenhagen S, Denmark.
Food Chem Toxicol. 2018 Jan;111:207-267. doi: 10.1016/j.fct.2017.11.020. Epub 2017 Nov 16.
Relatively few studies are available on realistic cumulative risk assessments for dietary pesticide exposure. Despite available studies showing low risk, public concern remains. A method to estimate realistic residue levels based on information from spraying journals and supervised residue trials was described in a previous publication. The present article proposes a new method to estimate average residue levels in imported foods based on residue monitoring data and knowledge about agronomic practices. The two methods were used in combination to estimate average pesticide residue levels in 47 commodities on the Danish market. The chronic consumer exposure was estimated in six Danish diets. The Hazard Index (HI) method was used to assess consumer risk. Despite the conservative (cautious) risk assessment approach, low HI values where obtained. The HI was 16% for adults and 44% for children, combining the risk of all pesticides in the diet.
the present study adds support to the evidence showing that adverse health effects of chronic pesticide residue exposure in the Danish population are very unlikely. The HI for pesticides for a Danish adult was on level with that of alcohol for a person consuming the equivalent of 1 glass of wine every seventh year.
关于饮食中农药暴露的实际累积风险评估，相关研究相对较少。尽管现有研究表明风险较低，但公众的担忧依然存在。之前的一篇文章中描述了一种基于喷洒杂志和监督残留试验信息来估计实际残留水平的方法。本文提出了一种基于残留监测数据和农业实践知识来估计进口食品中平均残留水平的新方法。这两种方法结合起来，估计了丹麦市场上 47 种商品中的平均农药残留水平。在六种丹麦饮食中估计了慢性消费者的暴露情况。采用危害指数（HI）方法评估消费者风险。尽管采用了保守（谨慎）的风险评估方法，但仍获得了较低的 HI 值。对于成年人和儿童（将饮食中的所有农药风险结合在一起），HI 值分别为 16%和 44%。
本研究为丹麦人群慢性农药残留暴露对健康产生不良影响的可能性非常小这一证据提供了支持。丹麦成年人的 HI 值与每年饮用相当于 1 杯葡萄酒的人摄入酒精的 HI 值相当。
