National Food Institute, Technical University of Denmark, Mørkhøj Bygade 19, 2860, Søborg, Denmark.
National Food Institute, Technical University of Denmark, Mørkhøj Bygade 19, 2860, Søborg, Denmark.
Food Chem Toxicol. 2022 Oct;168:113359. doi: 10.1016/j.fct.2022.113359. Epub 2022 Aug 12.
The cumulative chronic dietary exposure for the Danish population were assessed using Danish food monitoring data for the period 2012-2017 and Danish food consumption data for the consumer groups children (age 1-2, age 4-6 and age 7-14 years), adults age 15-75, high consumers and consumers eating Danish produced fruit and vegetables whenever possible. Levels below the Limit of Reporting (LOR) were set to ½ LOR with correction. For risk assessment of the cumulative chronic dietary exposure we used the Hazard Index (HI) method where the Hazard Quotient (HQ) was calculated for each pesticide and summed up to a HI. The HI was calculated to be below 1 for all consumer groups; i.e. 0.36 for children age 4-6 years and 0.13 for adults, indicating that the cumulative chronic dietary pesticide exposure is unlikely to constitute a health risk for Danish consumers, even for high consumers eating 600 g or more of fruit and vegetables each day. By eating Danish produced commodities whenever possible, the HI was reduced by a factor of one third for both children and adults. 25 different commodities contributed to about 90% of the HI and to 84% of the exposure.
丹麦人群的累积慢性膳食暴露情况通过 2012-2017 年丹麦食品监测数据和儿童（1-2 岁、4-6 岁和 7-14 岁）、15-75 岁成年人、高消费人群以及尽可能食用丹麦产水果和蔬菜的消费者群体的丹麦食品消费数据进行评估。低于报告限值 (LOR) 的水平设定为经修正后的 LOR 的一半。对于累积慢性膳食暴露的风险评估，我们使用危害指数 (HI) 方法，为每种农药计算危害商 (HQ)，并将其加总得到 HI。对于所有消费者群体，HI 均低于 1，即 4-6 岁儿童为 0.36，成年人 0.13，表明即使对于每天食用 600 克或更多水果和蔬菜的高消费人群，累积慢性膳食农药暴露也不太可能对丹麦消费者的健康构成风险。通过尽可能食用丹麦产商品，儿童和成年人的 HI 分别降低了三分之一。25 种不同的商品对 HI 的贡献约为 90%，对暴露量的贡献约为 84%。
