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与妊娠相关的复发性尿崩症:病理生理学与治疗

Recurrent diabetes insipidus associated with pregnancy: pathophysiology and therapy.

作者信息

Hughes J M, Barron W M, Vance M L

机构信息

Department of Internal Medicine, University of Virginia Medical Center, Charlottesville.

出版信息

Obstet Gynecol. 1989 Mar;73(3 Pt 2):462-4.

PMID:2915875
Abstract

Diabetes insipidus during pregnancy is an uncommon medical problem. We present a woman who developed transient central diabetes insipidus during two successive pregnancies. A water deprivation study with plasma arginine vasopressin concentrations confirmed the diagnosis and established the efficacy of 1-desamino-8-d-arginine-vasopressin (dDAVP). The patient was then successfully and safely treated through the second pregnancy with dDAVP.

摘要

妊娠期尿崩症是一种罕见的医学问题。我们报告一位女性,她在连续两次妊娠期间发生了短暂性中枢性尿崩症。一项通过检测血浆精氨酸加压素浓度的禁水试验确诊了该疾病,并确定了1-去氨基-8-D-精氨酸加压素(dDAVP)的疗效。随后,该患者在第二次妊娠期间通过dDAVP得到了成功且安全的治疗。

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