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为性别和性取向多元个体保留生育潜力。

Preservation of Fertility Potential for Gender and Sex Diverse Individuals.

作者信息

Johnson Emilie K, Finlayson Courtney

机构信息

Division of Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

出版信息

Transgend Health. 2016 Jan 1;1(1):41-44. doi: 10.1089/trgh.2015.0010. eCollection 2016.

DOI:10.1089/trgh.2015.0010
PMID:29159296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5685253/
Abstract

Gender and sex diverse individuals-transgender individuals and those with disorders of sex development (DSD)-both face medical treatments that may impair biological fertility potential. Young DSD patients also often have abnormal gonadal development. Fertility preservation for these populations has historically been poorly understood and rarely addressed. Future fertility should be discussed with gender and sex diverse individuals, particularly given recent advances in fertility preservation technologies and evolving views of fertility potential. Key ethical issues include parental proxy decision-making and uncertainty regarding prepubertal fertility preservation technologies. Many opportunities exist for advancing fertility-related care and research for transgender and DSD patients.

摘要

性别和性取向多元的个体——跨性别者和性发育障碍(DSD)患者——都面临着可能损害生物生育潜力的医学治疗。年轻的DSD患者通常也存在性腺发育异常的情况。历史上,对于这些人群的生育力保存了解甚少,也很少有人提及。应该与性别和性取向多元的个体讨论未来的生育问题,特别是考虑到生育力保存技术的最新进展以及对生育潜力不断变化的看法。关键的伦理问题包括父母代理决策以及青春期前生育力保存技术的不确定性。对于跨性别者和DSD患者,在推进与生育相关的护理和研究方面存在许多机会。

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1
Preservation of Fertility Potential for Gender and Sex Diverse Individuals.为性别和性取向多元个体保留生育潜力。
Transgend Health. 2016 Jan 1;1(1):41-44. doi: 10.1089/trgh.2015.0010. eCollection 2016.
2
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Clin Pract Pediatr Psychol. 2021 Dec;9(4):372-383. doi: 10.1037/cpp0000373. Epub 2020 Dec 3.
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Fertility preservation for transgender children and young people in paediatric healthcare: a systematic review of ethical considerations.儿童和青少年跨性别者生育力保存的儿科保健中的伦理考量:系统评价。
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本文引用的文献

1
Fertility Preservation in Children and Adolescents.儿童和青少年的生育力保存
Endocrinol Metab Clin North Am. 2015 Dec;44(4):799-820. doi: 10.1016/j.ecl.2015.07.005. Epub 2015 Sep 4.
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Progress and prospects for fertility preservation in prepubertal boys with cancer.癌症青春期前男孩生育力保存的进展与前景
Curr Opin Endocrinol Diabetes Obes. 2015 Jun;22(3):203-8. doi: 10.1097/MED.0000000000000162.
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Curr Opin Obstet Gynecol. 2014 Oct;26(5):372-80. doi: 10.1097/GCO.0000000000000107.
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J Clin Oncol. 2013 Jul 1;31(19):2500-10. doi: 10.1200/JCO.2013.49.2678. Epub 2013 May 28.
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Eur J Endocrinol. 2013 Mar 15;168(4):R67-76. doi: 10.1530/EJE-12-0934. Print 2013 Apr.
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Excessive androgen exposure in female-to-male transsexual persons of reproductive age induces hyperplasia of the ovarian cortex and stroma but not polycystic ovary morphology.在处于生育年龄的女性转男性变性人(transsexual persons)中,过多的雄激素暴露会导致卵巢皮质和间质增生,但不会导致多囊卵巢形态。
Hum Reprod. 2013 Feb;28(2):453-61. doi: 10.1093/humrep/des385. Epub 2012 Nov 27.
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