Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , CB 7431, Chapel Hill, North Carolina 27599-7431, United States.
Department of Statistics & Operations Research, University of North Carolina at Chapel Hill , CB 3260, Chapel Hill, North Carolina 27599-3260, United States.
Environ Sci Technol. 2017 Dec 19;51(24):14047-14054. doi: 10.1021/acs.est.7b03319. Epub 2017 Dec 1.
Azaarenes are N-heterocyclic polyaromatic pollutants that co-occur with polycyclic aromatic hydrocarbons (PAHs) in contaminated soils. Despite the known toxicity of some high-molecular-weight azaarenes, their diversity, abundance, and fate in contaminated soils remain to be elucidated. We applied high-resolution mass spectrometry and mass-defect filtering to four PAH-contaminated samples from geographically distant sites and detected 232 azaarene congeners distributed in eight homologous series, including alkylated derivatives and two hitherto unknown series. Four- and five-ring azaarenes were detected among these series, and the most abundant nonalkylated congeners groups (CHN, CHN, CHN, CHN, and CHN) were quantified. The profiles of congener groups varied among different sites. Three-ring azaarenes presented higher concentrations in unweathered sites, while four- and five-ring azaarenes predominated in weathered sites. Known toxic and carcinogenic azaarenes, such as benzo[c]acridine and dibenzo[a,h]acridine, were detected along with their multiple isomers. Our results highlight a previously unrecognized diversity and abundance of azaarenes in PAH-contaminated sites, with corresponding implications for environmental monitoring and risk assessment.
氮杂芳烃是与多环芳烃（PAHs）共同存在于污染土壤中的 N-杂环多环芳烃污染物。尽管一些高分子量氮杂芳烃具有已知的毒性，但它们在污染土壤中的多样性、丰度和归宿仍有待阐明。我们应用高分辨率质谱和质量亏损过滤技术，对来自地理位置遥远的四个 PAH 污染样本进行了分析，共检测到分布在八个同系物系列中的 232 种氮杂芳烃同系物，包括烷基化衍生物和两个迄今未知的系列。在这些系列中检测到了四环和五环氮杂芳烃，并且对最丰富的非烷基化同系物组（CHN、CHN、CHN、CHN 和 CHN）进行了定量分析。同系物组的分布在不同地点有所不同。三环氮杂芳烃在未风化的地点浓度较高，而四环和五环氮杂芳烃则在风化的地点占主导地位。还检测到了已知的有毒和致癌氮杂芳烃，如苯并[c]吖啶和二苯并[a,h]吖啶，以及它们的多种异构体。我们的研究结果突出了氮杂芳烃在 PAH 污染场所的多样性和丰富性，这对环境监测和风险评估具有相应的意义。
