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患者报告的身体活动与头颈部癌症幸存者健康相关生活质量的关联。

Patient-reported physical activity and the association with health-related quality of life in head and neck cancer survivors.

机构信息

Department of Otolaryngology-Head and Neck Surgery, VU University Medical Center, PO BOX 7057, 1007 MB, Amsterdam, The Netherlands.

Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

Support Care Cancer. 2018 Apr;26(4):1087-1095. doi: 10.1007/s00520-017-3926-y. Epub 2017 Nov 21.

Abstract

PURPOSE

This study aimed to assess patient-reported levels of physical activity (PA) and its associations with health-related quality of life (HRQoL) adjusted for important demographic, lifestyle-related, and clinical factors, among head and neck (HNC) survivors.

METHODS

This cross-sectional study included 116 HNC survivors. PA was assessed with the Physical Activity Scale for the Elderly (PASE) and HRQoL with the EORTC-QLQ-C30 and EORTC-HN35. Associations were studied using univariable and multivariable regression analyses.

RESULTS

Median PASE score was 100.3 (interquartile range 65.1;170.8) of which 54% were household, 34% leisure-time, and 12% occupational activities. Younger HNC survivors had higher levels of PA. Higher PA was significantly associated with higher global QoL (p < 0.05). Findings for physical function, role function, social function, fatigue, and pain were in line, but not statistically significant (0.05 ≤ p < 0.10).

CONCLUSIONS

Among HNC survivors, a large proportion of PA consists of household activities. Younger HNC survivors had higher PA levels, and higher PA levels were associated with higher HRQoL.

摘要

目的

本研究旨在评估头颈部(HNC)幸存者的体力活动(PA)水平及其与健康相关生活质量(HRQoL)的相关性,同时调整重要的人口统计学、生活方式相关和临床因素。

方法

本横断面研究纳入了 116 名 HNC 幸存者。采用老年人体力活动量表(PASE)评估 PA,采用 EORTC-QLQ-C30 和 EORTC-HN35 量表评估 HRQoL。采用单变量和多变量回归分析研究相关性。

结果

PASE 评分中位数为 100.3(四分位距 65.1;170.8),其中 54%为家务活动,34%为休闲时间活动,12%为职业活动。年轻的 HNC 幸存者体力活动水平较高。较高的 PA 与较高的总体 QoL 显著相关(p<0.05)。身体功能、角色功能、社会功能、疲劳和疼痛的结果一致,但无统计学意义(0.05≤p<0.10)。

结论

在 HNC 幸存者中,体力活动的很大一部分由家务活动组成。年轻的 HNC 幸存者体力活动水平较高,较高的体力活动水平与较高的 HRQoL 相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b919/5847044/b8af02c87d4d/520_2017_3926_Fig1_HTML.jpg

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