Longo W E, Zucker K A, Zdon M J, Modlin I M
Department of Surgery, West Haven VA Medical Center, Connecticut 06516.
Am Surg. 1989 Feb;55(2):100-4.
Early Gastric Cancer (EGC) is defined as tumor invasion limited to the mucosa and submucosa, irrespective of regional lymph node involvement. These patients have five-year survival rates in excess of 90 per cent. Although frequently seen in Japan, the detection of ECG remains uncommon in the United States. Twenty-two patients with EGC over a 15-year period were reviewed. EGC was identified in 0.5 per cent (1/207) of all gastric cancers before the widespread use of endoscopy (1972-1979) in our institution and in 16.5 per cent (21/127) of such patients after endoscopy began to replace barium contrast studies (1980-1987). Radiographic studies were performed initially in 14 out of 22 patients with EGC, and in ten patients were reported as normal. Endoscopy was used to make the diagnosis of EGC in 21 of 22 patients. Nineteen of the 22 patients are currently alive and free of disease (86%) with a mean follow-up of 3.4 years (range 6 months to 12 years). Our experience has paralleled that of the Japanese in that, with the adoption of fiberoptic endoscopy as the first-line diagnostic modality in patients with GI complaints, the detection of EGC has significantly increased.
早期胃癌（EGC）的定义为肿瘤浸润局限于黏膜层和黏膜下层，无论区域淋巴结是否受累。这些患者的五年生存率超过90%。虽然在日本较为常见，但在美国，EGC的检出率仍然较低。我们回顾了15年间22例EGC患者的情况。在我们机构广泛使用内镜检查之前（1972 - 1979年），EGC在所有胃癌中占0.5%（1/207），在内镜检查开始取代钡剂造影检查后（1980 - 1987年），此类患者中EGC占16.5%（21/127）。22例EGC患者中，最初有14例进行了影像学检查，其中10例报告正常。22例患者中有21例通过内镜检查确诊为EGC。22例患者中有19例目前存活且无疾病（86%），平均随访3.4年（范围6个月至12年）。我们的经验与日本人相似，即随着将纤维内镜检查作为胃肠道不适患者的一线诊断方法，EGC的检出率显著提高。
