Mailles A, Noel H, Pannetier D, Rapp C, Yazdanpanah Y, Vandentorren S, Chaud P, Philippe J M, Worms B, Bruyand M, Tourdjman M, Nahon M, Belchior E, Lucas E, Durand J, Zurbaran M, Vaux S, Coignard B, DE Valk H, Baize S, Quelet S, Bourdillon F
French National Public Health Agency,Saint-Maurice,France.
French Reference Center for Viral Hemorrhagic Fevers,Lyon,France.
Epidemiol Infect. 2017 Dec;145(16):3455-3467. doi: 10.1017/S0950268817002552. Epub 2017 Nov 23.
Introduction An unprecedented outbreak of Ebola virus diseases (EVD) occurred in West Africa from March 2014 to January 2016. The French Institute for Public Health implemented strengthened surveillance to early identify any imported case and avoid secondary cases.
Febrile travellers returning from an affected country had to report to the national emergency healthcare hotline. Patients reporting at-risk exposures and fever during the 21st following day from the last at-risk exposure were defined as possible cases, hospitalised in isolation and tested by real-time polymerase chain reaction. Asymptomatic travellers reporting at-risk exposures were considered as contact and included in a follow-up protocol until the 21st day after the last at-risk exposure.
From March 2014 to January 2016, 1087 patients were notified: 1053 were immediately excluded because they did not match the notification criteria or did not have at-risk exposures; 34 possible cases were tested and excluded following a reliable negative result. Two confirmed cases diagnosed in West Africa were evacuated to France under stringent isolation conditions. Patients returning from Guinea (n = 531; 49%) and Mali (n = 113; 10%) accounted for the highest number of notifications.
No imported case of EVD was detected in France. We are confident that our surveillance system was able to classify patients properly during the outbreak period.
引言 2014年3月至2016年1月,西非爆发了前所未有的埃博拉病毒病(EVD)疫情。法国公共卫生研究所实施了强化监测,以尽早发现任何输入性病例并避免二代病例出现。
从受影响国家返回的发热旅行者必须向国家紧急医疗热线报告。在最后一次高危暴露后第21天内报告有高危暴露且发热的患者被定义为可能病例,予以隔离住院并通过实时聚合酶链反应进行检测。报告有高危暴露的无症状旅行者被视为接触者,并纳入随访方案,直至最后一次高危暴露后第21天。
2014年3月至2016年1月,共报告1087例患者:1053例因不符合报告标准或无高危暴露而立即被排除;34例可能病例经检测且结果可靠为阴性后被排除。在严格隔离条件下,两名在西非确诊的病例被疏散至法国。从几内亚返回的患者(n = 531;49%)和从马里返回的患者(n = 113;10%)报告数量最多。
法国未检测到埃博拉病毒病输入性病例。我们相信我们的监测系统在疫情期间能够对患者进行正确分类。