Klein R, Klein B E, Moss S E, Davis M D, DeMets D L
Department of Ophthalmology, University of Wisconsin Medical School, Madison.
Arch Ophthalmol. 1989 Feb;107(2):237-43. doi: 10.1001/archopht.1989.01070010243030.
Population-based epidemiologic data on the incidence and progression of diabetic retinopathy are important in medical counseling and rehabilitative services and for developing approaches to preventing diabetic retinopathy. We performed a population-based study in southern Wisconsin of insulin-taking diabetic persons diagnosed before 30 years of age. Of the 271 who had no retinopathy at the first visit, 160 (59%) developed it by the time they were reexamined four years later, and 75 (11%) of the 713 free of proliferative diabetic retinopathy developed it. Overall, worsening of retinopathy occurred in 41% of the population, whereas improvement occurred in only 7%. The incidence of proliferative retinopathy rose with increasing duration until 13 to 14 years of diabetes, thereafter remaining between 14% and 17%. These incidence data underscore the need for careful ophthalmologic follow-up of these people.
基于人群的糖尿病视网膜病变发病率和进展的流行病学数据，对于医疗咨询、康复服务以及制定预防糖尿病视网膜病变的方法都非常重要。我们在威斯康星州南部对30岁之前被诊断为糖尿病且正在接受胰岛素治疗的人群进行了一项基于人群的研究。在首次就诊时没有视网膜病变的271人中，160人（59%）在四年后复查时出现了视网膜病变，在713例无增殖性糖尿病视网膜病变的患者中，有75人（11%）出现了该病变。总体而言，41%的人群视网膜病变恶化，而仅有7%的人群病情有所改善。增殖性视网膜病变的发病率随着糖尿病病程的延长而上升，直至糖尿病病程达到13至14年，此后发病率维持在14%至17%之间。这些发病率数据强调了对这些人群进行仔细眼科随访的必要性。
