Pandey Avinash, Suskin Neville, Poirier Paul
Cambridge Cardiac Care Centre, Cambridge, Ontario, Canada; Department of Medicine, Harvard Medical School, Boston, Massachusetts; University of Western Ontario, London, Ontario, Canada.
University of Western Ontario, London, Ontario, Canada.
Can J Cardiol. 2017 Dec;33(12):1645-1651. doi: 10.1016/j.cjca.2017.09.019. Epub 2017 Oct 6.
The impact of burst high-intensity exercise on physiological, cardiometabolic, and biochemical variables compared with traditional moderate-intensity continuous exercise training (MICT) has yet to be assessed in patients with type 2 diabetes (T2D). We compared the impact of multiple short-duration, high-intensity burst exercise sessions to MICT on cardiometabolic variables in patients with T2D.
Forty newly diagnosed patients with T2D not receiving lipid lowering or hypoglycemic medications were randomized to 40 minutes of MICT (60% of maximal heart rate) 5 days per week or 3 continuous bursts of 12 minutes of high-intensity exercise (85% of maximal heart rate) 5 days per week for 3 months. Body mass index, hemoglobin A (HbA), and lipid profile were assessed before and after 3 months of exercise training.
Burst exercise resulted in greater body mass index reduction than did MICT (-2.1 ± 1.2 kg/m vs -0.7 ± 0.7 kg/m, respectively; P < 0.05). There was a greater reduction at 3 months (P < 0.05) in HbA levels in the burst exercise group (8.14% ± 0.49% to 7.32% ± 0.39%) compared with the MICT group (8.18% ± 0.35% to 7.94% ± 0.41%). Compared with MICT, burst exercise was associated with a greater reduction in low-density lipoprotein cholesterol (-11 vs -4%; P < 0.05) and a greater increase in high-density lipoprotein cholesterol (22% vs 3%; all P < 0.05). After 3 months, patients in the burst exercise group attained greater exercise time on the treadmill (exercise capacity) than did those prescribed MICT (6.87 ± 1.44 minutes vs 5.40 ± 1.96 minutes; P < 0.001).
Findings from the current study support better cardiometabolic benefits of burst exercise compared with MICT over 3 months in patients with newly diagnosed T2D.
相较于传统的中等强度持续运动训练（MICT），爆发式高强度运动对2型糖尿病（T2D）患者生理、心脏代谢及生化指标的影响尚未得到评估。我们比较了多次短时长、高强度爆发式运动与MICT对T2D患者心脏代谢指标的影响。
40例新诊断的未接受降脂或降糖药物治疗的T2D患者被随机分为两组，一组每周5天进行40分钟的MICT（最大心率的60%），另一组每周5天进行3组持续12分钟的高强度运动（最大心率的85%），为期3个月。在运动训练3个月前后评估体重指数、糖化血红蛋白（HbA）和血脂谱。
爆发式运动导致的体重指数降低幅度大于MICT（分别为-2.1±1.2kg/m²和-0.7±0.7kg/m²；P<0.05）。与MICT组（8.18%±0.35%至7.94%±0.41%）相比，爆发式运动组在3个月时HbA水平降低幅度更大（P<0.05）（从8.14%±0.49%降至7.32%±0.39%）。与MICT相比，爆发式运动与低密度脂蛋白胆固醇的更大幅度降低（-11%对-4%；P<0.05）和高密度脂蛋白胆固醇的更大幅度升高（22%对3%；所有P<0.05）相关。3个月后，爆发式运动组患者在跑步机上的运动时间（运动能力）比接受MICT的患者更长（6.87±1.44分钟对5.40±1.96分钟；P<0.001）。
本研究结果支持，在新诊断的T2D患者中，与MICT相比，爆发式运动在3个月内对心脏代谢有更好的益处。
