Wood Gina, Murrell Anna, van der Touw Tom, Smart Neil
School of Science and Technology, University of New England, Armidale, New South Wales, Australia.
School of Rural Medicine, University of New England, Armidale, New South Wales, Australia.
BMJ Open Sport Exerc Med. 2019 Dec 17;5(1):e000647. doi: 10.1136/bmjsem-2019-000647. eCollection 2019.
To compare the effects of moderate intensity continuous training (MICT) and high intensity interval training (HIIT) on adult lipid profiles; to identify training or participant characteristics that may determine exercise-induced change in total cholesterol (TC), triglycerides (TRG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C).
Systematic review and meta-analysis.
English language searches of several databases were conducted from inception until September 2019.
Inclusion: (1) published randomised controlled human trials with group population n≥5; (2) intervention duration ≥4 weeks; (3) comparing HIIT with MICT; and (4) reporting pre-post intervention lipid measurements. Exclusion: subjects with chronic disease, <18 years, pregnant/lactating, in elite athletic training; and studies with a dietary or pharmaceutical intervention component.
Twenty-nine data sets (mmol/L) of 823 participants were pooled and analysed. Neither HIIT nor MICT was better in decreasing TC (0.10 (-0.06 to 0.19), p=0.12, I=0%), TRG (-0.05 (-0.11 to 0.01), p=0.10, I=0%), LDL-C (0.05 (-0.06 to 0.17), p=0.37, I=0%), or TC/HDL-C (-0.03 (-0.36 to 0.29), p=0.85, I=0%). HIIT significantly raised HDL-C (0.07 (0.04 to 0.11), p<0.0001, I=0%) compared with MICT.
Neither HIIT nor MICT is superior for altering TC, TRG, or LDL-C, or TC-HDL-C ratio. Compared with MICT, HIIT appeared to significantly improve HDL-C. Clinicians may prescribe either protocol to encourage participation in exercise and reduce cardiovascular risk. To raise HDL-C, HIIT may result in a larger effect size compared with MICT.
CRD42019136722.
比较中等强度持续训练（MICT）和高强度间歇训练（HIIT）对成人血脂谱的影响；确定可能决定运动引起的总胆固醇（TC）、甘油三酯（TRG）、高密度脂蛋白胆固醇（HDL-C）和低密度脂蛋白胆固醇（LDL-C）变化的训练或参与者特征。
系统评价和荟萃分析。
从数据库建立至2019年9月进行了英文文献检索。
纳入标准：（1）已发表的随机对照人体试验，每组人群n≥5；（2）干预持续时间≥4周；（3）比较HIIT与MICT；（4）报告干预前后的血脂测量值。排除标准：患有慢性病、年龄<18岁、怀孕/哺乳期、参加精英运动训练的受试者；以及包含饮食或药物干预成分的研究。
汇总并分析了823名参与者的29个数据集（mmol/L）。HIIT和MICT在降低TC（0.10（-0.06至0.19），p=0.12，I=0%）、TRG（-0.05（-0.11至0.01），p=0.10，I=0%）、LDL-C（0.05（-0.06至0.17），p=0.37，I=0%）或TC/HDL-C（-0.03（-0.36至0.29），p=0.85，I=0%）方面均无优势。与MICT相比，HIIT显著提高了HDL-C（0.07（0.0
