Wu C T, Pei X T, Cong P J
Department of Experimental Hematology, Beijing Institute of Radiation Medicine, China.
Exp Hematol. 1989 Mar;17(3):304-8.
Two kinds of HL-60 cell growth suppressor present in human fetal liver were studied. One is the already known arginase, which showed nonspecific suppression on the growth of HL-60 cells and human granulocyte-macrophage progenitors (CFU-GM), and the other, a new species of suppressor with the characteristics of lower molecular weight (less than 10,000 daltons), shows preferential suppression on HL-60 cell growth, but less effect on the growth of CFU-GM.
对人胎肝中存在的两种HL - 60细胞生长抑制因子进行了研究。一种是已知的精氨酸酶,它对HL - 60细胞和人粒细胞 - 巨噬细胞祖细胞(CFU - GM)的生长表现出非特异性抑制作用;另一种是一种新的抑制因子,具有低分子量(小于10,000道尔顿)的特性,对HL - 60细胞生长表现出优先抑制作用,但对CFU - GM的生长影响较小。