Acrocomia aculeata Kernel Oil 对 2 型糖尿病大鼠肥胖的影响。
Effect of Acrocomia aculeata Kernel Oil on Adiposity in Type 2 Diabetic Rats.
机构信息
Post-Graduate Program in Biotechnology and Biodiversity Pro-Midwest Network, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, 79070-900, Brazil.
Post-Graduate Program in Biotechnology, Universidade Católica Dom Bosco, Campo Grande, MS, Brazil.
出版信息
Plant Foods Hum Nutr. 2018 Mar;73(1):61-67. doi: 10.1007/s11130-017-0648-8.
The macauba palm (Acrocomia aculeata) is native of tropical America and is found mostly in the Cerrados and Pantanal biomes. The fruits provide an oily pulp, rich in long chain fatty acids, and a kernel that encompass more than 50% of lipids rich in medium chain fatty acids (MCFA). Based on biochemical and nutritional evidences MCFA is readily catabolized and can reduce body fat accumulation. In this study, an animal model was employed to evaluate the effect of Acrocomia aculeata kernel oil (AKO) on the blood glucose level and the fatty acid deposit in the epididymal adipose tissue. The A. aculeata kernel oil obtained by cold pressing presented suitable quality as edible oil. Its fatty acid profile indicates high concentration of MCFA, mainly lauric, capric and caprilic. Type 2 diabetic rats fed with that kernel oil showed reduction of blood glucose level in comparison with the diabetic control group. Acrocomia aculeata kernel oil showed hypoglycemic effect. A small fraction of total dietary medium chain fatty acid was accumulated in the epididymal adipose tissue of rats fed with AKO at both low and high doses and caprilic acid did not deposit at all.
巴西栗（Acrocomia aculeata）原产于美洲热带地区，主要分布在塞拉多和潘塔纳尔生物群落。其果实含有丰富的油性果肉和长链脂肪酸，以及富含中链脂肪酸（MCFA）的种仁，占比超过 50%。基于生化和营养证据，MCFA 很容易被代谢，并能减少体内脂肪堆积。在这项研究中，我们采用动物模型来评估巴西栗种仁油（AKO）对血糖水平和附睾脂肪组织中脂肪酸沉积的影响。冷榨获得的巴西栗种仁油可作为食用油，其脂肪酸组成表明 MCFA 含量高，主要是月桂酸、癸酸和己酸。与糖尿病对照组相比，喂食该种仁油的 2 型糖尿病大鼠的血糖水平降低。巴西栗种仁油具有降血糖作用。无论是低剂量还是高剂量喂食 AKO，大鼠的附睾脂肪组织中仅积累了一小部分膳食中的总 MCFA，而己酸则根本没有沉积。
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