Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Devision of Dermatology, Tokoname City Hospital, Tokoname, Japan.
J Dermatol. 2018 Mar;45(3):353-356. doi: 10.1111/1346-8138.14146. Epub 2017 Nov 27.
Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is very rare, with only 61 cases reported to date. EMPSGC is considered to be a low-grade carcinoma of sweat gland origin. Dermoscopic findings of EMPSGC have not been previously reported. We report the first case of a man with EMPSGC, featuring dermoscopic findings. Dermoscopic examinations of the present EMPSGC lesion revealed tumor cell proliferation that appeared as pink ovoid nests and elongated epidermis that resembled a whitish-pink network. Another characteristic finding of the present lesion was the large red/blue globules in pink ovoid nests in the tumor. Those reflected lacunae containing secretory fluid with red blood cells. We think that the large red/blue globules in pink ovoid nests in our case could be a characteristic dermoscopic finding specific to EMPSGC. We dermatologists encounter many "pink nodules" at out-patient clinics. The present dermoscopic findings may be useful for the differential diagnosis of EMPSGC.
内分泌黏液性汗腺癌（EMPSGC）非常罕见，迄今为止仅报告了 61 例。EMPSGC 被认为是一种低级别汗腺来源的癌。EMPSGC 的皮肤镜表现尚未有报道。我们报告首例男性 EMPSGC 的皮肤镜表现。本 EMPSGC 病变的皮肤镜检查显示肿瘤细胞增殖，表现为粉红色的卵圆形巢和类似乳白色网络的延长表皮。本病变的另一个特征性发现是粉红色卵圆形巢中的大红色/蓝色球体。这些反映了含有红细胞的分泌液的腔隙。我们认为，我们病例中粉红色卵圆形巢中的大红色/蓝色球体可能是 EMPSGC 的特征性皮肤镜表现。我们皮肤科医生在门诊经常遇到许多“粉红色结节”。本皮肤镜表现可能有助于 EMPSGC 的鉴别诊断。
