Zhang Le, Zhang Chenghua, Yang Zhaoying, He Miao, Zhang Lijuan, Ezzat Shereen, Liang Xi
Department of Breast Surgery, China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.
Endoscopy Department, Jilin Cancer Hospital, Changchun, Jilin, China.
Onco Targets Ther. 2017 Nov 14;10:5459-5462. doi: 10.2147/OTT.S151260. eCollection 2017.
Occult breast cancer is defined by the presence of axillary metastases without an identifiable primary breast tumor. Here, we report a rare case of a male occult breast cancer with dermatomyositis. We performed a modified radical mastectomy consisting of whole breast mastectomy and axillary lymph node dissection. Immunohistochemistry and fluorescent in situ hybridization analyses demonstrated an adenocarcinoma likely of breast origin, which was an occult triple-negative breast cancer. Interestingly, the patient's previously noted periorbital dermatomyositis resolved promptly following surgical excision.
隐匿性乳腺癌的定义为存在腋窝转移但未发现原发性乳腺肿瘤。在此，我们报告一例罕见的男性隐匿性乳腺癌合并皮肌炎病例。我们实施了改良根治性乳房切除术，包括全乳切除术和腋窝淋巴结清扫术。免疫组织化学和荧光原位杂交分析显示为可能起源于乳腺的腺癌，即隐匿性三阴性乳腺癌。有趣的是，患者先前出现的眶周皮肌炎在手术切除后迅速缓解。
