Ranmadugala Dinali, Ebrahiminezhad Alireza, Manley-Harris Merilyn, Ghasemi Younes, Berenjian Aydin
Faculty of Science & Engineering, University of Waikato, Hamilton, New Zealand.
Department of Medical Biotechnology, School of Medicine, and Noncommunicable Diseases Research Centre, Fasa University of Medical Sciences, Fasa, Iran.
Biotechnol Lett. 2018 Feb;40(2):237-248. doi: 10.1007/s10529-017-2477-0. Epub 2017 Nov 27.
Bacterial cell immobilization is a novel technique used in many areas of biosciences and biotechnology. Iron oxide nanoparticles have attracted much attention in bacterial cell immobilization due to their unique properties such as superparamagnetism, large surface area to volume ratio, biocompatibility and easy separation methodology. Adhesion is the basis behind many immobilization techniques and various types of interactions determine bacterial adhesion. Efficiency of bacterial cell immobilization using iron oxide nanoparticles (IONs) generally depends on the physicochemical properties of the IONs and surface properties of bacterial cells as well as environmental/culture conditions. Bacteria exhibit various metabolic responses upon interaction with IONs, and the potential applications of iron oxide nanoparticles in bacterial cell immobilization will be discussed in this work.
细菌细胞固定化是一种应用于生物科学和生物技术诸多领域的新技术。氧化铁纳米颗粒因其具有超顺磁性、高比表面积、生物相容性以及易于分离等独特性质，在细菌细胞固定化方面备受关注。粘附是许多固定化技术的基础，多种相互作用决定了细菌的粘附。使用氧化铁纳米颗粒（IONs）进行细菌细胞固定化的效率通常取决于IONs的物理化学性质、细菌细胞的表面性质以及环境/培养条件。细菌与IONs相互作用时会表现出各种代谢反应，本文将讨论氧化铁纳米颗粒在细菌细胞固定化中的潜在应用。
