Acibadem Mehmet Ali Aydinlar University, School of Medicine, Neurology Department, Turkey.
Acibadem Mehmet Ali Aydinlar University, School of Medicine, Neurology Department, Turkey.
Mult Scler Relat Disord. 2018 Jan;19:96-98. doi: 10.1016/j.msard.2017.11.011. Epub 2017 Nov 20.
Cocaine abuse may cause stroke, metabolic or multifocal inflammatory leukoencephalopathy. We described a patient with cocaine abuse who presented with Balo's type acute multifocal leukoencephalopathy. Magnetic Resonance Imaging (MRI) of the brain showed onion like patchy concentric ring enhancement on T1-weighted MRI with gadolinium. Balo's Concentric Sclerosis like radiological findings related to cocaine has not been reported. Levamisole is now frequently used as an ingredient in cocaine and may cause leukoencephalopathy. It is recommended to check urine levamisole levels in patients with cocaine-induced leukoencephalopathy with or without mimicking Balo's Concentric Sclerosis. On the other hand, it is also possible that the cocaine use was coincidental and this was a demyelinating case arising de novo in patient who uses cocaine.
可卡因滥用可能导致中风、代谢性或多灶性炎症性脑白质病。我们描述了一位可卡因滥用患者，其表现为 Balo 型急性多灶性脑白质病。脑磁共振成像（MRI）显示 T1 加权 MRI 上呈洋葱状斑片状同心环状增强，钆增强后更明显。与可卡因相关的 Balo 样同心性硬化的放射学发现尚未见报道。左旋咪唑现在经常被用作可卡因的成分，可能导致脑白质病。建议在可卡因诱导的脑白质病患者中检查尿液左旋咪唑水平，无论是否模仿 Balo 样同心性硬化。另一方面，也有可能是巧合的，这位使用可卡因的患者新发脱髓鞘病例。
