Yang Xiaoyu, Liu Xiaoliang, Li Wensen, Chen Dawei
Department of Neurosurgery, First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Oncol Lett. 2016 Nov;12(5):3417-3422. doi: 10.3892/ol.2016.5119. Epub 2016 Sep 12.
Pituicytoma is a rare tumor of the sellar and suprasellar regions, arising from the pituicytes, which are specialized glial cells in the neurohypophysis and infundibulum. Due to its rarity, ambiguity persists over the diagnosis, management and prognosis of pituicytoma. The current study presents a case series of three patients, each with a histopathological diagnosis of pituicytoma. A summary of the clinical manifestations, radiological characteristics, histopathological features, treatment strategies and prognoses are presented. In addition, 78 cases of pituicytoma, identified in a search of the published literature in Pubmed, are profiled. Pituicytoma typically presents with dysfunction of the optic nerve and pituitary. The radiological characteristics are nonspecific; diagnosis is typically made on the basis of histopathological results. The tumor is slow growing and benign and is amenable to surgical treatment by gross total resection; subsequent tumor recurrence is rare. A definitive assessment of prognosis requires an extended follow-up in a larger cohort.
垂体细胞瘤是一种罕见的鞍区和鞍上区肿瘤，起源于垂体细胞，垂体细胞是神经垂体和漏斗部的特殊神经胶质细胞。由于其罕见性，垂体细胞瘤的诊断、管理和预后仍存在模糊性。本研究报告了3例病例系列，每例均经组织病理学诊断为垂体细胞瘤。文中呈现了临床表现、放射学特征、组织病理学特征、治疗策略和预后的总结。此外，还对在PubMed上检索到的78例垂体细胞瘤病例进行了分析。垂体细胞瘤通常表现为视神经和垂体功能障碍。放射学特征不具有特异性；诊断通常基于组织病理学结果。该肿瘤生长缓慢且为良性，可通过全切除手术治疗；随后肿瘤复发罕见。对预后进行明确评估需要在更大的队列中进行长期随访。
