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医院间甲状腺切除术特定结局的差异及其与风险调整和医院绩效的关联。

Variation of Thyroidectomy-Specific Outcomes Among Hospitals and Their Association With Risk Adjustment and Hospital Performance.

机构信息

American College of Surgeons, Chicago, Illinois.

Department of Surgery, University of Chicago Medicine, Chicago, Illinois.

出版信息

JAMA Surg. 2018 Jan 17;153(1):e174593. doi: 10.1001/jamasurg.2017.4593.

Abstract

IMPORTANCE

Current surgical quality metrics might be insufficient to fully judge the quality of certain operations because they are not procedure specific. Hypocalcemia, recurrent laryngeal nerve (RLN) injury, and hematoma are considered to be the most relevant outcomes to measure after thyroidectomy. Whether these outcomes can be used as hospital quality metrics is unknown.

OBJECTIVES

To evaluate whether thyroidectomy-specific outcomes vary among hospitals, whether the addition of thyroidectomy-specific variables affects risk adjustment, and whether differences in hospital performance are associated with thyroidectomy-specific care processes.

DESIGN, SETTING, AND PARTICIPANTS: In this retrospective cohort study, patients undergoing thyroidectomies from January 1, 2013, through December 31, 2015, at hospitals participating in the American College of Surgeons' National Surgical Quality Improvement Program were studied.

EXPOSURE

Thyroidectomy-related care.

MAIN OUTCOMES AND MEASURES

Clinically severe hypocalcemia, RLN injury, and clinically significant hematoma within 30 days of thyroid surgery and hospital-level performance variation, change in risk adjustment, and association with processes.

RESULTS

Overall, 14 540 patients (mean [SD] age, 52.1 [15.0] years; 11 499 [79.1%] female) underwent operations at 98 hospitals. Because operations missing thyroidectomy-specific outcomes were excluded, the numbers of operations and hospitals analyzed differed by outcome. Of 14 540 operations included, clinically severe hypocalcemia occurred in 450 patients (3.3% overall, 0.6% after partial, and 4.7% after subtotal or total thyroidectomy), RLN injury in 755 patients (5.7% overall, 4.2% after partial, and 6.6% after subtotal or total thyroidectomy), and hematoma in 175 patients (1.3%). Hospital performance varied for hypocalcemia and RLN injury but not for hematoma. Hospital performance rankings were largely unaffected by the inclusion of thyroidectomy-specific data in risk adjustment. With regard to processes, patients undergoing thyroidectomies at the best-performing vs worst-performing hospitals less frequently had their postoperative parathyroid hormone level measured (593 [19.9%] vs 457 [31.7%], P < .001) and more often were prescribed oral calcium, vitamin D, or both (2281 [76.6%] vs 962 [66.8%], P < .001). When profiled by RLN injury, use of energy devices (1517 [69.1%] vs 507 [55.2%], P < .001) and intraoperative nerve monitoring (1223 [55.7%] vs 346 [37.7%], P < .001) were more prevalent at the best- compared with the worst-performing hospitals.

CONCLUSIONS AND RELEVANCE

Postoperative hypocalcemia and RLN injury, but not hematoma, potentially could be used as thyroidectomy-specific national hospital quality improvement metrics. Strategies aimed at reducing these complications after thyroidectomy may improve the care of these patients.

摘要

重要性

目前的外科质量指标可能不足以全面评估某些手术的质量,因为它们不是针对特定手术的。低钙血症、喉返神经(RLN)损伤和血肿被认为是甲状腺手术后最重要的评估结果。这些结果是否可以用作医院质量指标尚不清楚。

目的

评估甲状腺切除术的特定结果是否因医院而异,添加甲状腺切除术特定变量是否会影响风险调整,以及医院绩效差异是否与甲状腺切除术特定护理过程相关。

设计、地点和参与者:在这项回顾性队列研究中,研究了 2013 年 1 月 1 日至 2015 年 12 月 31 日期间在美国外科医师学院国家外科质量改进计划参与医院接受甲状腺切除术的患者。

暴露因素

与甲状腺切除术相关的护理。

主要结果和测量指标

甲状腺手术后 30 天内临床严重低钙血症、RLN 损伤和临床显著血肿,以及医院层面的绩效变化、风险调整的变化和与过程的相关性。

结果

共有 14540 名患者(平均[标准差]年龄为 52.1[15.0]岁;11499[79.1%]名女性)在 98 家医院接受了手术。由于排除了缺少甲状腺切除术特定结果的手术,分析的手术和医院数量因结果而异。在纳入的 14540 例手术中,450 例(总体 3.3%,部分切除后 0.6%,次全或全切除后 4.7%)发生临床严重低钙血症,755 例(总体 5.7%,部分切除后 4.2%,次全或全切除后 6.6%)发生 RLN 损伤,175 例(1.3%)发生血肿。低钙血症和 RLN 损伤的医院绩效存在差异,但血肿无差异。医院绩效排名在很大程度上不受在风险调整中纳入甲状腺切除术特定数据的影响。在手术过程方面,在表现最好的医院和表现最差的医院接受甲状腺切除术的患者,其术后甲状旁腺激素水平检测的可能性较低(593[19.9%]例比 457[31.7%]例,P < .001),更常服用口服钙、维生素 D 或两者(2281[76.6%]例比 962[66.8%]例,P < .001)。当按 RLN 损伤情况进行分析时,能量设备的使用(1517[69.1%]例比 507[55.2%]例,P < .001)和术中神经监测(1223[55.7%]例比 346[37.7%]例,P < .001)在表现最好的医院比表现最差的医院更为常见。

结论和相关性

术后低钙血症和 RLN 损伤,但不是血肿,可能可作为甲状腺切除术特定的全国医院质量改进指标。旨在减少甲状腺切除术后这些并发症的策略可能会改善这些患者的护理。

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