Wentz Travis G, Muruvanda Tim, Lomonaco Sara, Thirunavukkarasu Nagarajan, Hoffmann Maria, Allard Marc W, Hodge David R, Pillai Segaran P, Hammack Thomas S, Brown Eric W, Sharma Shashi K
Division of Microbiology, Office of Regulatory Science, Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, Maryland, USA.
Chemical and Biological Defense Division, Department of Homeland Security, Washington, DC, USA.
Genome Announc. 2017 Nov 30;5(48):e01296-17. doi: 10.1128/genomeA.01296-17.
Clostridial neurotoxins, including botulinum and tetanus neurotoxins, are among the deadliest known bacterial toxins. Until recently, the horizontal mobility of this toxin gene family appeared to be limited to the genus We report here the closed genome sequence of , a Gram-negative bacterium containing coding sequences with homology to clostridial neurotoxin family proteins.
梭菌神经毒素，包括肉毒杆菌神经毒素和破伤风神经毒素，是已知最致命的细菌毒素之一。直到最近，这个毒素基因家族的水平转移似乎仅限于梭菌属。我们在此报告一种革兰氏阴性细菌的完整基因组序列，该细菌含有与梭菌神经毒素家族蛋白具有同源性的编码序列。
