Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, State-Local Joint Engineering Laboratory for Novel Functional Polymer Materials, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, China.
Angew Chem Int Ed Engl. 2018 Jan 22;57(4):1053-1056. doi: 10.1002/anie.201710811. Epub 2017 Dec 20.
Nanostructured polyion complexes (PICs) are appealing in biomaterials applications. Yet, conventional assembly suffers from the weakness in scale-up and reproducibility. Only a few low-dimensional PICs are available to date. Herein we report an efficient and scalable strategy to prepare libraries of low-dimensional PICs. It involves a visible-light-mediated RAFT polymerization of ionic monomer in the presence of a polyion of the opposite charge at 5-50 % w/w total solids concentration in water at 25 °C, namely, polymerization-induced electrostatic self-assembly (PIESA). A Vesicle, multi-compartmental vesicle, and large-area unilamellar nanofilm can be achieved in water. A long nanowire and porous nanofilm can be prepared in methanol/water. An unusual unimolecular polyion complex (uPIC)-sphere-branch/network-film transition is reported. This green chemistry offers a general platform to prepare various low-dimensional PICs with high reproducibility on a commercially viable scale under eco-friendly conditions.
纳米结构聚离子复合物（PICs）在生物材料应用中具有吸引力。然而，传统的组装方法在规模扩大和重现性方面存在弱点。迄今为止，只有少数几种低维 PICs 可用。本文报道了一种高效、可扩展的策略，用于制备低维 PIC 库。它涉及在可见光介导下，在 25°C 的水中，在 5-50%w/w 总固体浓度下，离子单体在带相反电荷的聚离子存在下进行可逆加成-断裂链转移（RAFT）聚合，即聚合诱导静电自组装（PIESA）。可以在水中得到囊泡、多腔囊泡和大面积的单分子层纳米薄膜。在甲醇/水中可以制备长纳米线和多孔纳米薄膜。报道了一种不寻常的单分子聚离子复合物（uPIC）-球支/网络薄膜转变。这种绿色化学为在商业上可行的规模和环保条件下，以高重现性制备各种低维 PIC 提供了一个通用平台。
