Ahluwalia P, Malik V B
Department of Biochemistry, Punjab University, Chandigarh, India.
Toxicol Lett. 1989 Feb;45(2-3):195-8. doi: 10.1016/0378-4274(89)90009-x.
Monosodium glutamate (MSG) was administered to adult male mice for 6 d at dose levels of 2, 4 and 8 mg/g b.w. Dose levels of 4 and 8 mg/g MSG resulted in significant changes in serum total lipids, triglycerides, phospholipids, free fatty acids and blood glucose 31 d after cessation of exposure. Administration of 2 mg/g MSG resulted in a decrease in blood glucose concentration but had no effect on the other measured end-points. No change in serum cholesterol was observed, either in free or esterified form or in different fractions of lipoproteins.
将味精(MSG)以2、4和8毫克/克体重的剂量水平给予成年雄性小鼠,持续6天。在停止暴露31天后,4和8毫克/克体重的味精剂量水平导致血清总脂质、甘油三酯、磷脂、游离脂肪酸和血糖发生显著变化。给予2毫克/克体重的味精导致血糖浓度降低,但对其他测量的终点指标没有影响。无论是游离形式还是酯化形式的血清胆固醇,以及脂蛋白的不同组分,均未观察到变化。