University of North Carolina Project-China, Guangzhou, China.
Medicine Department, Yale University School of Medicine, New Haven, Connecticut, USA.
AIDS. 2018 Jan 28;32(3):371-381. doi: 10.1097/QAD.0000000000001705.
HIV self-testing (HIVST) is now officially recommended by the WHO, yet much of HIVST evidence to date has focused on quantitative data and hypothetical concerns. Effective scale-up of HIVST in diverse local contexts requires qualitative data from experiences using and organizing HIVST. This qualitative systematic review aims to appraise and synthesize research evidence on experiences using and organizing HIVST.
We conducted a systematic search of seven primary literature databases, four gray literature sources, and reference lists reporting qualitative evidence on HIVST. Data extraction and thematic analysis were used to synthesize findings. Quality of studies was assessed using the Critical Appraisal Skills Programme tool. Confidence in review findings was evaluated using the Confidence in the Evidence from Reviews of Qualitative Research approach. The review protocol was registered (CRD42015027607).
From 1266 potential articles, we included 18. Four studies were conducted in low-income countries, three in middle-income countries, 10 in high-income countries, and one in multiple countries. Generally, HIVST increased capacity to reach priority populations and expanded opportunities for service delivery. Self-testing was preferred to facility-based testing due to increased convenience and confidentiality, especially among stigmatized populations. HIVST decreased test-associated stigma compared with facility-based testing. HIVST generally empowered people because it provided greater control over individual testing needs. At the same time, HIVST rarely allowed husbands to coerce their wives to test.
This review suggests that HIVST should be offered as an additional HIV testing option to expand testing and empower testers. Adapting national policies to incorporate HIVST will be necessary to guide scale-up.
世界卫生组织(WHO)现已正式推荐艾滋病病毒自检(HIVST),但迄今为止,HIVST 的大部分证据都集中在定量数据和假设性问题上。要在不同的当地环境中有效推广 HIVST,需要使用和组织 HIVST 的经验方面的定性数据。本定性系统评价旨在评估和综合使用和组织 HIVST 的经验方面的研究证据。
我们对七个主要文献数据库、四个灰色文献来源以及报告 HIVST 定性证据的参考文献进行了系统搜索。使用数据提取和主题分析来综合研究结果。使用关键评估技能计划工具评估研究的质量。使用来自定性研究评价的证据的信心评估方法评估审查结果的置信度。审查方案已注册(CRD42015027607)。
从 1266 篇潜在文章中,我们纳入了 18 篇。四项研究在低收入国家进行,三项在中等收入国家进行,十项在高收入国家进行,一项在多个国家进行。一般来说,HIVST 增加了接触重点人群的能力,并扩大了服务提供的机会。由于便利性和保密性提高,与基于机构的检测相比,自我检测更受青睐,特别是在受污名化的人群中。与基于机构的检测相比,HIVST 减少了与检测相关的污名。HIVST 通常使人们更有权力,因为它提供了对个人检测需求的更大控制。与此同时,HIVST 很少允许丈夫强迫妻子进行检测。
本综述表明,应该将 HIVST 作为扩大检测和赋予检测者权力的额外 HIV 检测选择提供。适应国家政策以纳入 HIVST 将是指导推广的必要条件。