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肿瘤患者的骨髓穿刺:来自儿科内部标准的经验。

Bone marrow aspirations in oncological patients: experience from an in-house standard in paediatrics.

作者信息

Sauer Harald, Graeber Stefan, Lieser Ulla, Foell Juergen

机构信息

Clinic for Pediatric Cardiology, University Hospital of Saarland, 66421, Homburg, Germany.

Institute of Medical Biometry, Epidemiology and Medical Computer Science, University Hospital of Saarland, Kirrberger Straße, Homburg (Saar), Germany.

出版信息

Wien Med Wochenschr. 2019 Mar;169(3-4):82-86. doi: 10.1007/s10354-017-0611-1. Epub 2017 Dec 1.

Abstract

BACKGROUND

Nearly all paediatric patients require deep sedation when undergoing bone marrow aspiration (BMA). We analyzed the data from our protocols documented in a standardised procedure for bone marrow puncture over a period of 2 years.

METHODS

Our standard included the documentation of personal data as well as vital parameters. In addition, we documented all medications administered, potential complications and required intervention measures, as necessary.

RESULTS

A total of 107 protocols were available for the evaluation. Our standard covered the usage of midazolam and S‑ketamine and resulted in complications in just 9 patients, which could be remedied using simple measures. For both active substances, the dosage necessary to reach sufficient deep analgosedation was significantly higher for patients under 24 months of age.

CONCLUSIONS

Our standard for BMA provides a practical and feasible procedure. In addition to good examination conditions, our standard also helps ensure the safety of our patients.

摘要

背景

几乎所有儿科患者在进行骨髓穿刺术(BMA)时都需要深度镇静。我们分析了在两年时间里按照标准化骨髓穿刺程序记录的方案数据。

方法

我们的标准包括记录个人数据以及生命体征参数。此外•我们还记录了所有给予的药物、潜在并发症以及必要时所需的干预措施。

结果

共有107份方案可供评估。我们的标准涵盖了咪达唑仑和S-氯胺酮的使用,仅9例患者出现并发症,可通过简单措施补救。对于这两种活性物质,24个月以下的患者达到足够深度镇痛镇静所需的剂量明显更高。

结论

我们的BMA标准提供了一个切实可行的程序。除了良好的检查条件外,我们的标准还有助于确保患者的安全。

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