West Malcolm A, Wischmeyer Paul E, Grocott Michael P W
Academic Unit of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Curr Anesthesiol Rep. 2017;7(4):340-349. doi: 10.1007/s40140-017-0245-2. Epub 2017 Nov 7.
The purpose of this study is to evaluate the role of physical exercise and nutrition interventions in adult patients before elective major surgery.
Exercise training before elective adult major surgery is feasible, safe, and efficacious, but the clinical effectiveness remains uncertain. Early data suggests a reduction in morbidity, length of stay, and quality of life, but the results of larger definitive studies are awaited. Nutritional interventions are less well evaluated and when they are, it is often in combination with exercise interventions as part of a prehabilitation package.
Studies evaluating exercise and nutrition interventions before elective major surgery in adults are producing encouraging early results, but definitive clinical evidence is currently very limited. Future research should focus on refining interventions, exploring mechanism, and evaluating the interactions between therapies and large-scale clinical effectiveness studies.
本研究旨在评估体育锻炼和营养干预在择期大手术成年患者中的作用。
择期成年大手术前的运动训练可行、安全且有效，但临床效果仍不确定。早期数据表明发病率、住院时间和生活质量有所降低，但仍有待更大规模确定性研究的结果。营养干预的评估较少，而且评估时通常是作为术前康复方案的一部分与运动干预相结合。
评估成人择期大手术前运动和营养干预的研究正在产生令人鼓舞的早期结果，但目前确凿的临床证据非常有限。未来的研究应侧重于优化干预措施、探索机制以及评估治疗之间的相互作用和大规模临床效果研究。
