从中国一例死亡病例中分离出的人类致病细菌菌株VV2014DJH的全基因组序列。
Complete genome sequence of the strain VV2014DJH, a human-pathogenic bacterium isolated from a death case in China.
作者信息
Pan Junhang, Sun Yi, Yao Wenwu, Mao Haiyan, Zhang Yanjun, Zhu Muyuan
机构信息
College of Life Sciences, Zhejiang University, Hangzhou, 310058 China.
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, 310051 China.
出版信息
Gut Pathog. 2017 Nov 21;9:67. doi: 10.1186/s13099-017-0216-7. eCollection 2017.
BACKGROUND
, an opportunistic pathogen, is the causative agent of life-threatening septicemia and severe wound infections. However, the pathogenicity and virulence factors of are not fully understood. Here we report the complete genome sequence of VV2014DJH, which was isolated from a death case.
RESULTS
The genome of the VV2014DJH contains two circular chromosomes with a mean G+C content of 46.8%, but does not consists of any plasmids. The chromosome I and chromosome II consist of 3,303,590 and 1,770,972 bp, respectively. In addition, the genome consists of 4617 protein coding genes, 172 RNA genes and type I, II and III secretion systems were predicted.
CONCLUSIONS
In this study, the genomic information of the VV2014DJH has been described. The information would contribute to the increasing scope and depth of genome database, and provide insights into the pathogenicity and virulence factors of .
背景
[病原体名称]是一种机会致病菌，是危及生命的败血症和严重伤口感染的病原体。然而，[病原体名称]的致病性和毒力因子尚未完全了解。在此，我们报告了从一例死亡病例中分离出的[病原体名称]VV2014DJH的完整基因组序列。
结果
[病原体名称]VV2014DJH的基因组包含两条环状染色体，平均G+C含量为46.8%，但不包含任何质粒。染色体I和染色体II分别由3,303,590和1,770,972个碱基对组成。此外，该基因组由4617个蛋白质编码基因、172个RNA基因组成，并预测存在I型、II型和III型分泌系统。
结论
在本研究中，描述了[病原体名称]VV2014DJH的基因组信息。这些信息将有助于扩大和深化[病原体名称]基因组数据库的范围，并为了解[病原体名称]的致病性和毒力因子提供见解。
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