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伊朗的乳腺癌状况:1998年至2014年间3010例病例的统计分析

Breast Cancer Status in Iran: Statistical Analysis of 3010 Cases between 1998 and 2014.

作者信息

Akbari Mohammad Esmaeil, Sayad Soheila, Sayad Saed, Khayamzadeh Maryam, Shojaee Leila, Shormeji Zeynab, Amiri Mojtaba

机构信息

Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Surgery, Firoozgar Clinical Research Development Center, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Int J Breast Cancer. 2017;2017:2481021. doi: 10.1155/2017/2481021. Epub 2017 Nov 1.

Abstract

BACKGROUND

Breast cancer is the 5th leading cause of cancer death in Iranian women. This study analyzed 3010 women with breast cancer that had been referred to a cancer research center in Tehran between 1998 and 2014.

METHODS

In this retrospective study, we analyzed 3010 breast cancer cases with 32 clinical and paraclinical attributes. We checked the data quality rigorously and removed any invalid values or records. The method was data mining (problem definition, data preparation, data exploration, modeling, evaluation, and deployment). However, only the descriptive analyses' results of the variables are presented in this article. To our knowledge, this is the most comprehensive study on breast cancer status in Iran.

RESULTS

A typical Iranian breast cancer patient has been a 40-50-year-old married woman with two children, who has a high school diploma and no history of abortion, smoking, or diabetes. Most patients were estrogen and progesterone receptor positive, human epidermal growth factor (HER) negative, and P53 negative. Most cases were detected in stage 2 with intermediate grade.

CONCLUSION

This study revealed original findings which can be used in national policymaking to find the best early detection method and improve the care quality and breast cancer prevention in Iran.

摘要

背景

乳腺癌是伊朗女性癌症死亡的第五大主要原因。本研究分析了1998年至2014年间转诊至德黑兰一家癌症研究中心的3010例乳腺癌女性患者。

方法

在这项回顾性研究中,我们分析了3010例具有32种临床和副临床特征的乳腺癌病例。我们严格检查了数据质量,去除了任何无效值或记录。方法是数据挖掘(问题定义、数据准备、数据探索、建模、评估和部署)。然而,本文仅呈现变量的描述性分析结果。据我们所知,这是关于伊朗乳腺癌状况最全面的研究。

结果

典型的伊朗乳腺癌患者是一名40至50岁、已婚、育有两个孩子、具有高中学历且无流产、吸烟或糖尿病史的女性。大多数患者雌激素和孕激素受体呈阳性,人表皮生长因子(HER)呈阴性,P53呈阴性。大多数病例在2期被检测出,分级为中级。

结论

本研究揭示了一些原始发现,可用于国家政策制定,以找到最佳的早期检测方法,并提高伊朗乳腺癌的护理质量和预防水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c78b/5671722/8237a7b69039/IJBC2017-2481021.001.jpg

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