Scott J, Wood G D
School of Dental Surgery, University of Liverpool, U.K.
Br J Oral Maxillofac Surg. 1989 Feb;27(1):53-9. doi: 10.1016/0266-4356(89)90127-7.
A case of an aggressive calcifying odontogenic cyst of the maxilla is presented. It recurred twice after surgical excision over the course of a year and was subsequently treated by maxillectomy followed by radiotherapy. The current histological criteria for the diagnosis of calcifying odontogenic cyst were satisfied but it is argued that they are drawn too widely. Since the majority of calcifying odontogenic cysts are benign in behaviour the presence of cytological indicators of local destruction and invasiveness alongside the usual features of calcifying odontogenic cysts (presence of dentinoid, epithelial ghost-cell degeneration) should be the over-riding prognostic considerations and should thus be reflected in the diagnostic title. Such tumours are best regarded as variants of ameloblastoma rather than as unusually aggressive forms of calcifying odontogenic cyst and an appropriate name would be 'dentinogenic ghost-cell ameloblastoma'.
本文报告一例上颌骨侵袭性钙化牙源性囊肿。该病例在手术切除后的一年内复发两次，随后接受了上颌骨切除术并辅以放疗。目前钙化牙源性囊肿的组织学诊断标准虽得到满足，但有人认为这些标准界定过于宽泛。鉴于大多数钙化牙源性囊肿的行为是良性的，除了钙化牙源性囊肿的常见特征（类牙本质、上皮影细胞变性）外，出现局部破坏和侵袭的细胞学指标应作为首要的预后考量因素，因此应在诊断名称中体现。这类肿瘤最好被视为成釉细胞瘤的变体，而非钙化牙源性囊肿的异常侵袭性形式，合适的名称应为“牙本质生成性影细胞成釉细胞瘤”。
