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土耳其慢性乙型肝炎患者中甲型肝炎病毒抗体的血清流行率

Seroprevalence of Hepatitis A Virus Antibodies among the Patients with Chronic Hepatitis B in Turkey.

作者信息

Tulek Necla, Ozsoy Metin, Moroglu Cigdem, Cagla Sonmezer Meliha, Temocin Fatih, Tuncer Ertem Gunay, Sebnem Erdinc Fatma

机构信息

Department of Infectious Diseases and Clinical Microbiology, Ankara Training and Research Hospital, Ankara, Turkey.

出版信息

Euroasian J Hepatogastroenterol. 2015 Jul-Dec;5(2):95-97. doi: 10.5005/jp-journals-10018-1143. Epub 2016 Jul 9.

DOI:10.5005/jp-journals-10018-1143
PMID:29201701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5578535/
Abstract

BACKGROUND

Hepatitis A virus (HAV) can cause significant pathology in patients with chronic hepatitis B virus (HBV), however, HAV can be prevented by vaccination. The aim of this study was to determine the implication of vaccination against HAV vaccine in patients with chronic hepatitis B.

MATERIALS AND METHODS

The seroprevalence of anti-HAV IgG antibodies was investigated in the patients with chronic hepatitis B. Anti-HAV IgG antibodies were detected by commercially available ELISA kit.

RESULTS

A total of 673 patients (354 males, 319 females with age range of 17-78 years) with chronic hepatitis B were included the study. Hepatitis A virus seropositivity rate was 34% in the patients younger than 20 years, 79% in the age group of 20 to 29 years, and 100% after 35 years of age.

DISCUSSION

Hepatitis A virus vaccination may be recommended for young adult patients with chronic hepatitis B in Turkey.

HOW TO CITE THIS ARTICLE

Tulek N, Ozsoy M, Moroglu C, Sonmezer MC, Temocin F, Ertem GT, Erdinc FS. Seroprevalence of Hepatitis A Virus Antibodies among the Patients with Chronic Hepatitis B in Turkey. Euroasian J Hepato-Gastroenterol 2015;5(2):95-97.

摘要

背景

甲型肝炎病毒（HAV）可在慢性乙型肝炎病毒（HBV）患者中引发严重病变，不过，可通过接种疫苗预防甲型肝炎病毒感染。本研究旨在确定甲型肝炎病毒疫苗接种对慢性乙型肝炎患者的影响。

材料与方法

对慢性乙型肝炎患者的抗甲型肝炎病毒IgG抗体血清流行率进行调查。采用市售酶联免疫吸附测定（ELISA）试剂盒检测抗甲型肝炎病毒IgG抗体。

结果

本研究共纳入673例慢性乙型肝炎患者（男性354例，女性319例，年龄范围为17 - 78岁）。20岁以下患者的甲型肝炎病毒血清阳性率为34%，20至29岁年龄组为79%，35岁以后为100%。

讨论

在土耳其，对于患有慢性乙型肝炎的年轻成年患者，可能建议接种甲型肝炎病毒疫苗。

如何引用本文

图莱克N，奥兹索伊M，莫罗格鲁C，松梅泽尔MC，特莫辛F，埃尔滕GT，埃尔丁奇FS。土耳其慢性乙型肝炎患者中甲型肝炎病毒抗体的血清流行率。《欧亚肝脏胃肠病学杂志》2015年；5(2):95 - 97。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e518/5578535/2cafbe5a063d/ejohg-05-095-i001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e518/5578535/2cafbe5a063d/ejohg-05-095-i001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e518/5578535/2cafbe5a063d/ejohg-05-095-i001.jpg

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