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孟加拉国一个茶园中乙肝病毒和丙肝病毒的流行情况

Prevalence of Hepatitis B Virus and Hepatitis C Virus in a Tea Garden of Bangladesh.

作者信息

Al Mahtab Mamun, Akhter Shamima, U Mollick Kutub, H Uddin Mohammad, I Khan Sakirul, Mf Akbar Sheikh

机构信息

Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Department of Physiology, Dhaka Medical College, Dhaka, Bangladesh.

出版信息

Euroasian J Hepatogastroenterol. 2017 Jan-Jun;7(1):107-110. doi: 10.5005/jp-journals-10018-1227. Epub 2017 May 5.

Abstract

INTRODUCTION

The overall health status of workers of tea garden of Bangladesh is below the national standard. Also, almost nothing has been reported about status of hepatitis virus infection among these population and there is also a lack of consensus.

MATERIALS AND METHODS

Several health-related facts, especially those of liver diseases, were collected from 130 workers of tea garden via questionnaire. Sera were also collected from these subjects to assess positivity of hepatitis B surface antigen (HBsAg) and antibody to hepatitis C virus (anti-HCV). Hepatitis B virus (HBV) genotype was also done using genotype-specific primers in HBsAg-positive sera.

RESULTS

Out of 130 tea garden workers, 5 were positive for HBsAg; however, none was reactive to anti-HCV. Genotyping of HBV deoxyribonucleic acid of 4 sera samples revealed that 2 belonged to genotype A, 1 to genotype C, and 1 to genotype D. Various risk factors were documented in HBV-infected subjects by analyzing the questionnaire.

CONCLUSION

Hepatitis B virus in considerable high percentage is prevalent among workers of tea garden in Bangladesh, and immediate vaccination against HBV should be employed. Also, health education system should be accentuated in specific population like tea garden workers. Al Mahtab M, Akhter S, Mollick KU, Uddin MH, Khan SI, Akbar SMF. Prevalence of Hepatitis B Virus and Hepatitis C Virus in a Tea Garden of Bangladesh. Euroasian J Hepato-Gastroenterol 2017;7(1):107-110.

摘要

引言

孟加拉国茶园工人的整体健康状况低于国家标准。此外,关于这些人群中肝炎病毒感染状况几乎没有报道,并且也缺乏共识。

材料与方法

通过问卷调查从130名茶园工人中收集了一些与健康相关的事实,尤其是肝脏疾病方面的。还从这些受试者中采集了血清,以评估乙肝表面抗原(HBsAg)和丙肝病毒抗体(抗-HCV)的阳性情况。对于HBsAg阳性血清,还使用基因型特异性引物进行了乙肝病毒(HBV)基因分型。

结果

在130名茶园工人中,5人HBsAg呈阳性;然而,无人抗-HCV呈阳性反应。对4份血清样本的HBV脱氧核糖核酸进行基因分型显示,2份属于A基因型,1份属于C基因型,1份属于D基因型。通过分析问卷记录了HBV感染受试者的各种风险因素。

结论

在孟加拉国茶园工人中,相当高比例的人感染乙肝病毒,应立即接种乙肝疫苗。此外,应加强针对茶园工人等特定人群的健康教育体系。Al Mahtab M、Akhter S、Mollick KU、Uddin MH、Khan SI、Akbar SMF。孟加拉国一个茶园中乙肝病毒和丙肝病毒的流行情况。《欧亚肝脏胃肠病学杂志》2017年;7(1):107 - 110。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fba/5663790/5b72fba9ef7a/ejohg-07-107-g001.jpg

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