包皮环切术男童中BXO与肥胖之间的关联
The Association Between BXO and Obesity in Boys Undergoing Circumcision.
作者信息
Fuchs Molly E, Beecroft Nicholas, Dajusta Daniel G, McLeod Daryl J
机构信息
Nationwide Children's Hospital, Columbus, OH, USA.
The OSU College of Medicine, Columbus, OH, USA.
出版信息
Glob Pediatr Health. 2017 Nov 24;4:2333794X17742749. doi: 10.1177/2333794X17742749. eCollection 2017.
This study investigated whether boys with balanitis xerotica obliterans (BXO) have increased rates of obesity compared with boys with no concern for BXO (NCB). Boys ≤18 years old with circumcision pathology-confirmed BXO were compared with an age-matched group who had NCB during circumcision. Boys with BXO were found to have a mean body mass index of 70.64 percentile for age compared with 52.43 percentile in age-matched controls ( = .0005). The rate of obesity was significantly higher in boys with BXO (42%) compared with 12.4% in boys with NCB (odds ratio = 5.12; 95% CI = 2.6 to 10.06). Given the increasing rates of childhood obesity and the long-term health consequences of both BXO and obesity, special attention should be paid to this population. Further research is needed to determine if BXO in obese children may represent an early indicator of a systemic disease process where intervention may be warranted.
本研究调查了患有闭塞性干燥性龟头炎（BXO）的男孩与无BXO相关问题（NCB）的男孩相比，肥胖率是否更高。将年龄≤18岁且经包皮环切病理确诊为BXO的男孩与在包皮环切时无BXO的年龄匹配组进行比较。结果发现，患有BXO的男孩的平均体重指数处于年龄的第70.64百分位，而年龄匹配的对照组为第52.43百分位（P = 0.0005）。患有BXO的男孩的肥胖率（42%）显著高于无BXO的男孩（12.4%）（优势比 = 5.12；95%置信区间 = 2.6至10.06）。鉴于儿童肥胖率不断上升以及BXO和肥胖对长期健康的影响，应特别关注这一人群。需要进一步研究以确定肥胖儿童中的BXO是否可能代表一种全身性疾病过程的早期指标，对此可能需要进行干预。
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