阻塞性睡眠呼吸暂停中上气道结构的解剖学测量
Anatomic measures of upper airway structures in obstructive sleep apnea.
作者信息
Barrera Jose E, Pau Candace Y, Forest Veronique-Isabelle, Holbrook Andrew B, Popelka Gerald R
机构信息
Division of Sleep Surgery, Department of Otolaryngology, Stanford University, USA.
出版信息
World J Otorhinolaryngol Head Neck Surg. 2017 Jun 21;3(2):85-91. doi: 10.1016/j.wjorl.2017.05.002. eCollection 2017 Jun.
OBJECTIVE
Determine if anatomic dimensions of airway structures are associated with airway obstruction in obstructive sleep apnea (OSA) patients.
METHODS
Twenty-eight subjects with ( = 14) and without ( = 14) OSA as determined by clinical symptoms and sleep studies; volunteer sample. Skeletal and soft tissue dimensions were measured from radiocephalometry and magnetic resonance imaging. The soft palate thickness, mandibular plane-hyoid (MP-H) distance, posterior airway space (PAS) diameters and area, and tongue volume were calculated.
RESULTS
Compared to controls, the OSA group demonstrated a significantly longer MP-H distance ( = 0.009) and shorter nasal PAS diameter ( = 0.02). The PAS area was smaller ( = 0.002) and tongue volume larger in the OSA group ( = 0.004). The MP-H distance, PAS measurements, and tongue volume are of clinical relevance in OSA patients.
CONCLUSIONS
A long MP-H distance, and small PAS diameters and area are significant anatomic measures in OSA; however the most substantial parameter found was a large tongue volume.
目的
确定气道结构的解剖学尺寸是否与阻塞性睡眠呼吸暂停（OSA）患者的气道阻塞相关。
方法
通过临床症状和睡眠研究确定28名有（n = 14）和无（n = 14）OSA的受试者；志愿者样本。通过X线头影测量法和磁共振成像测量骨骼和软组织尺寸。计算软腭厚度、下颌平面-舌骨（MP-H）距离、后气道间隙（PAS）直径和面积以及舌体积。
结果
与对照组相比，OSA组的MP-H距离显著更长（P = 0.009），鼻PAS直径更短（P = 0.02）。OSA组的PAS面积更小（P = 0.002），舌体积更大（P = 0.004）。MP-H距离、PAS测量值和舌体积在OSA患者中具有临床相关性。
结论
MP-H距离长、PAS直径和面积小是OSA的重要解剖学指标；然而，发现的最主要参数是舌体积大。
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