巴雷特食管腺癌：一种被高估的风险。
Adenocarcinoma in Barrett's oesophagus: an overrated risk.
作者信息
Van der Veen A H, Dees J, Blankensteijn J D, Van Blankenstein M
机构信息
Department of Internal Medicine II, University Hospital Rotterdam, The Netherlands.
出版信息
Gut. 1989 Jan;30(1):14-8. doi: 10.1136/gut.30.1.14.
Abstract
Barrett's oesophagus is a risk factor for the development of oesophageal cancer and for this reason annual endoscopic surveillance has been proposed. In this retrospective study of all patients with Barrett's oesophagus diagnosed in a 12 year period carcinoma had developed in only four patients. The incidence of oesophageal cancer in this series was one in 170 patient years, which means a 30-fold increase compared with the general population. The survival of patients with Barrett's oesophagus was not different, however, from an age and sex matched control population. It is concluded that systematic endoscopic surveillance of patients with Barrett's oesophagus is not indicated.
摘要
巴雷特食管是食管癌发生的一个危险因素，因此有人提议进行年度内镜监测。在这项对12年间诊断出的所有巴雷特食管患者的回顾性研究中，只有4例患者发生了癌变。该系列中食管癌的发病率为每170患者年1例，这意味着与普通人群相比增加了30倍。然而，巴雷特食管患者的生存率与年龄和性别匹配的对照人群并无差异。结论是，不建议对巴雷特食管患者进行系统的内镜监测。
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