Santos Mauricéa Tabósa Ferreira, Guerra Gutemberg, de Menezes Terce Liana, Carvalho Tatiana Lins, Alchieri João Carlos, Sougey Everton Botelho
Occupational Therapist, gerontologist and doctorate student in the Postgraduate Program of Health Sciences (UFRN).
Neurologist, Master in Neuropsychiatry and coordinator of Behavioral and Cognitive Neurology Outpatient Facility (UFPE).
Dement Neuropsychol. 2008 Oct-Dec;2(4):333-338. doi: 10.1590/S1980-57642009DN20400018.
In the differential diagnosis between Alzheimer's disease (AD) and normal aging, tests evaluating memory and executive functions are frequently used. The addition of abstraction tests may enhance the effectiveness of screening tests for AD.
The aim of this study was to compare initial data of a new instrument - The Screening Test for Alzheimer's Disease with Proverbs (STADP) - against other screening tests used in AD diagnosis.
Sixty elderly individuals (46 controls and 14 AD subjects with CDR=1), aged =60 years, with at least one year of schooling, were evaluated using the STADP at outpatient clinic. The STADP assesses short-term memory, episodic memory, executive functions and language, in addition to proverb recognition. The performance of the participants on the Mini-Mental State Examination (MMSE), semantic Verbal Fluency (VF) and Clock Drawing Test (CDT) were evaluated and the habit of reading, writing and sociodemographic data were also taken into account.
There were significant correlations between STADP and the performance on the MMSE (r=0.64), CDT (r=0.50) and VF (r=0.56). Age influenced all sub-items of the STADP, specifically episodic memory (r= -0.54), whereas schooling mainly influenced executive functions and language (r=0.46). The total score, stages A and C and the "proverb recognition" of STADP (p<0.001), as well as the MMSE (p<0.001), CDT (p=0.016), VF (p<0.001) were significantly different in AD versus control groups.
The findings point to the potential use of the STADP in AD, warranting the conducting of further studies.
在阿尔茨海默病（AD）与正常衰老的鉴别诊断中，经常使用评估记忆和执行功能的测试。增加抽象测试可能会提高AD筛查测试的有效性。
本研究的目的是将一种新工具——阿尔茨海默病谚语筛查测试（STADP）的初始数据与AD诊断中使用的其他筛查测试进行比较。
60名年龄≥60岁、至少接受过一年教育的老年人（46名对照者和14名CDR = 1的AD患者）在门诊使用STADP进行评估。STADP除了评估谚语识别外，还评估短期记忆、情景记忆、执行功能和语言。评估了参与者在简易精神状态检查表（MMSE）、语义言语流畅性（VF）和画钟测试（CDT）中的表现，并考虑了阅读、写作习惯和社会人口统计学数据。
STADP与MMSE（r = 0.64）、CDT（r = 0.50）和VF（r = 0.56）的表现之间存在显著相关性。年龄影响STADP的所有子项目，特别是情景记忆（r = -0.54），而受教育程度主要影响执行功能和语言（r = 0.46）。AD组和对照组在STADP的总分、A和C阶段以及“谚语识别”（p < 0.001），以及MMSE（p < 0.001）、CDT（p = 0.016）、VF（p < 0.001）方面存在显著差异。
研究结果表明STADP在AD中具有潜在用途，值得进行进一步研究。
